If you type in one of these codes as a seed, you can play a special run with unique features. Unlike normal seeds, the floor layout will be different each time. However, achievements & unlocks will be temporarily disabled.
Effect Password All enemies are friendly towards you. (Flies spawned by Duke of Flies die instantly, but Dingle's dingleberries do not) CLSTRPHO All enemies have permanent fear effect. FEARM1NT All pill names and descriptions show ???. MED1C1NE All sound effects are replaced with the sound of a fart. FARTSNDS All tarot cards are face down when picked up (So they have an unknown effect). FACED0WN All walk and shoot keys have been reversed. DRAWKCAB Applies a filter that makes the game look like it's being played through a cathode ray tube. B00BT00B Basement repeats infinitely. BASEMENT Character and their tears turn completely black. PTCHBLCK Character has no face. THEBLANK Character is completely invisible to the player. IMNOBODY Character leaves a trail of poop behind him as he walks. BRWNSNKE Character spawns as grey, in reference to the Twitch emote. KAPPA Character takes damage if they stop moving. DONTSTOP Character/Enemies/Hazards/Items/Consumables blend into floor. WHOAWHAT Enemies are dazed. C0NFETT1 Enemies are invisible (including bosses, fires, etc). BL1NDEYE Enemies respawn once player leaves cleared room (includes bosses). New items won't drop. COMEBACK Enemies won’t take damage. All doors stay open. When in a boss room, you must wait until the bosses health slowly drains before you can move on. PAC1F1SM Enemies won’t take damage. All doors stay open. When in a boss room, you must wait until the bosses health slowly drains before you can move on. PAC1F1ST Every 45 seconds, a ticking will begin, and after 5 seconds, Isaac will take 1/2 heart of damage. Having invincibility overrides the damage. THEGHOST Every few seconds all enemies gain fear effect. FRA1DN0T Everything does at least one full heart of damage. HARDHARD Get hit by one enemy that does damage and you die. Similar to playing as The Lost. BRTLB0NS Ingame text is rearranged as though the character has trouble reading/speaking. DYSLEXIA Ingame text is rearranged as though the character has trouble reading/speaking. DYSLEXIC Isaac wears a Santa hat. CHRSTMAS Isaac's head is large. T0PHEAVY Isaac's head is small. T1NYD0ME Items mimic character movement (doesn't affect troll bombs). KEEPAWAY Makes a lot more blood appear after death of the enemies. BLOOOODY Makes all enemies charmed permanently. COCKFGHT Makes co-op babies invincible. K1DSM0DE Music is slowed ANDANTE Music is sped up. ALLEGR0 Music is sped up. PREST0 Music is super slowed. LARGHET0 Music playback speed/pitch is affected by character's walking speed. SLOW4ME2 Neither the map nor the health bar can be seen. KEEPTRAK No gold rooms spawn. GGGGGGGG Start with 69 coins and the player must pay for every item. FREE2PAY Start with 69 coins and the player must pay for every item. PAY2PLAY Tears glow TEARGL0W The lower your health is, the slower the music is. HARTBEAT Turns all enemies into their champion versions (if they have one). CHAMP10N Turns character invisible. CAMOK1DD Turns enemies invisible. CAM0F0ES Turns pick-ups invisible. CAMODROP You leave a pee puddle when entering a room. PEE Your character wears a Santa hat. HOHOHOHO
Contributed By: -Unowninator-.
The are multiple characters that can be unlocked in the game, each requiring you to fulfill a certain condition during a play-through.
Note: You can only unlock characters in regular, random runs. Meeting the requirements in a challenge or manually inputting a random seed will not allow you to unlock characters (indicated by the no trophy icon below your stats).
Unlockable How to Unlock ??? (The Blue Baby) Reward for defeating Mom's Heart for the 10th time. Azazel Make three deals with the devil during a run. Cain Have 55 or more pennies at any time during a run. Eden Reward for defeating Mom's Heart for the first time. Eve Complete two consecutive floors without picking up any hearts (including Soul, Black, and Eternal Hearts) Judas Unlocked when you defeat Satan the first time. Lazarus Have 4 or more Soul and/or Black Hearts at any time during a run. Magdalene Have 7 or more Red Heart Containers at any time in a run Samson Complete two consecutive floors without taking any damage. The Lost Have any character kill themselves while holding the Missing Poster in a Self-Sacrifice Room, using the spikes in the centre.
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