What do you need help on? Cancel X

Jump to:
Would you recommend this Guide? Yes No Hide
Send Skip Hide

FAQ/Walkthrough by miyuandfay

Version: 1.0 | Updated: 04/01/12

 _____   __   __   ___
|_   _| |  | |  | |  _|
  | |   |  |_|  | | |_
  | |   |   _   | |  _|
  | |   |  | |  | | |_
  |_|   |__| |__| |___|

	 ____   _____   ___     _   ___    _____   ___     _    ____
  	|    \ |_   _| |   \   | | | _ \  |_   _| |   \   | |  / ___\
	| [] / 	 | |   | |\ \  | | | |\ \   | |   | |\ \  | | | /  ___
	|   |    | |   | | \ \ | | | | | |  | |   | | \ \ | | | | |_ _|
	| [] \  _| |_  | |  \ \| | | |/ /  _| |_  | |  \ \| | |  \_/ /
  	|____/ |_____| |_|   \___| |___/  |_____| |_|   \___|  \____/

   _ _   _   _
| / / \ / \ /
| \ |_| |_| |
|_/ | | | | \_
/O O\

Copywright: Edmund McMillen, 2011
Walkthrough/FAQ Written By: Alex Forman
Email: weareformans@hotmail.com
version 1.0


1) Intro
2) Controls
3) Basic Walkthrough
--3a) The Basement
--3b) The Caves
--3c) The Depths
--3d) Chapter 4
--3e) Chapter 5
4) Character List
5) Enemy List
6) Boss List
7) Room List
8) Dungeon Features
9) Items List
10) Achievements and Unlockables
11) Sample playthrough

INTRODUCTION                   |

The Binding of Isaac is action/shooter dungeon crawler heavily influenced by
Legend of Zelda with roughe elements and pretty much everything you've ever
wanted in this style of game. Since The Binding of Isaac is heavily randomized,
it will be impossible to predict what you'll see or receive at any time in the
game, but I'll be doing my best to make navigating the unknown as easy as

A HUGE thanks to all the people at the Binding of Isaac wiki for providing
access to information that would have taken so much more to find.

The story of the Binding of Isaac is simple yet devious.
Isaac lives at home with his mother in a small house atop a small hill. Isaac's
mother spends her time obsessing in religious broadcast television paying
little or no mind to Isaac.
One day, Isaac's mother hears the voice of God. God informs her that Isaac has
become corrupted by sin and must be cleansed.
Isaac's mother takes from him all of his personal possessions; his toys, his
drawings, his clothes; and locks Isaac in his room.
But the voice of God is not satisfied, he requires a sacrifice of Isaac for his
mother to prove her devotion.
Determined not to fail God, Isaac's mother grabs a butchers knife and prepares
to kill her son.
Seeing his immenant doom approaching, Isaac searches desperately for a means of
Finding a trapdoor leading into the basement beneath the rug, Isaac plunges
into the depths just before his mother bursts through the door.
Cold and alone, Isaac's only choice is to delve deeper into the darkness,
facing his fears and insecurities and, ultimately, his mother.

CONTROLS                       |

The Binding of Isaac utilizes the keyboard (or dual stick analog controllers if
you have one) in order to play. Alternate mouse/keyboard controls are also
\_\_\_\|  Basic Movement - Up, Down, Left and Right. Navigate the rooms to
your heart's content

\_\_\_\| Attack - Sends a single tear flying in the chosen cardinal direction.
Hold for rapid fire (see "Tears" section of stats). The trajectory of your
tears adhere to Newton's laws, so tears will retain any velocity you had at the
time of firing; that is to say moving to the west while firing north will cause
the tear to move on a north-west trajectory; moving and firing in opposite
directions will slow tears and reduce range; moving and firing in the same
direction will speed up tears and increase range.

\______\| Use Item - If you possess an activatable item, pressing space will
activate it. See activated items.
 _         _____
|E|\      |SHIFT|\
\_\| OR  \______\| Drops a bomb at the player's feet if you have one. See
items for more info on bombs.

\_\| Use Card/Pill - If you are currently carrying a Tarot Card or a Pill of
any kind, this will consume that item and produce an effect. See items for more
information on Tarot Cards and Pills.

SAVING - The Binding of Isaac DOES NOT have normal saving like some games. If
you die, it's game over and you'll have to try again, however the game DOES
have an autosave feature that tracks stats (such as items found/discovered and
achievements unlocked). Never quit the Binding of Isaac through any method
other than the "Exit Game" option on the main menu or you may lose some
BASIC WALKTHROUGH              |
Quick tip - If you see this, there is some general strategy or helpful info
provided. Even if you aren't planning on reading its particular section of the
walkthrough, take the time to read these as they often apply to later floors as

Welcome to the basement, you've officially descended into what will either be
your salvation or your death depending on how your luck and skills pan out.
You will automatically start in an empty room with the game's controls
conveniently scrawled on the floor before you. Assuming this is your first
playthrough you should take note of you current HP and any bombs or cash you
may be starting with (depends on character).
Working under the assumption that you're playing with Isaac, you should have a
bomb to start with. DONT WASTE IT NOW.

Bombs and keys can be dropped, bought and found in chests. You occasionally
start with one if your character includes it. In early levels you can go whole
floors without finding ANY of either so use them wisely.

A word from the wise - This game is randomized quite a bit, the room layouts
and types will vary and the enemies and bosses spawning will as well. Nothing I
can do will tell you what will be in your dungeon besides what is not
randomized so from here on out it's strategy and assumption.

From this room there may be doors extending out into one to four other
Take a quick note of your HUD and menu options, get a handle on the shooting
controls and limber up. The more ready you are for the next room, the less
likely you'll get hurt. Don't get hurt.

On this floor, enemies will be relatively easy, ranging from flies that follow
you (red), flies that just buzz around (black), hopping corpses (minus a head
O_O), floating heads (minus a body o_o), zombies (sometimes without eyes x_x)
and all manner of horrible things which you can read about in the bestiary
later... or now if you want to skip ahead.

Rooms on this floor are typically the most basic types. From this point on
until any level past the depths 2, every floor will ALWAYS have the following
(including floor 1)
-A Treasure room (always locked except for basement 1)
-A Shop (always locked)
-A boss room (never locked)
-A "Secret" room (not on the map, blocked by a breakable wall that can be
opened with a bomb)

Floor 1 treasure rooms are never locked

Familiarize yourself with pills and Tarot cards if you'd like, otherwise use
this guide as a reference.

Rooms on the Basement 1 will typically contain either enemies, items, chests or
a combination thereof.
Any room with enemies will lock upon entry, after clearing, the room will
unlock and an item or chest MAY spawn in the center of the room.

Enemies on this floor will typically be pushovers with minimal AI. Some enemies
will not deal touch damage, though most of these enemies will spawn flies on
being killed, so expect the unexpected.

Explore the level as you can, leaving behind any items or chests that cannot be
reached without a key or bomb. Make your way to the treasure room, which will
have a golden crown on the map and a golden door on the screen. This room will
almost ALWAYS be your first destination on EVERY floor from here on out and you
should ALWAYS keep a key on hand for future treasure rooms.

This floor will typically have about 10 rooms to explore.

A quick monster guide to the basement:
-Flies (in all varieties)
-Clot (not to be confused with Clotty) AKA Mini-Gish

A Treasure room ALWAYS contains a free treasure which is either a Passive,
Activated, or Familiar/Orbital (See items)

Speaking of keys...
If you find a key it has 3 primary uses:
Open Shops
Open golden chests
Open keystones

On floor one only the first is a guarantee and with little or no cash it's not

Shops contain anything from hearts to treasures. Every item has a default price
and a sale price (which is approximately 50% off). As to which price an item
takes is random, but the base price for item types is static. If keys are
scarce, keep this in mind: A treasure in a shop will cost 15 coins, 7 if it's
on sale, so unless you are crossing your fingers for something else, entering a
shop with any less is usually a waste unless you are looking for Greed (see

This floor may also contain a mini-boss which will be announced by a fanfare
and sudden change in music. Mini-bosses are usually one of the Seven Deadly
Sins (see below) and should not be taken lightly early in the game. If you
encounter one, feel free to pause, run to this guide and be prepared to fight.
It helps to know a boss' moves and attacks.

Explore your current floor to its fullest, keeping in mind that somewhere a
secret room is hidden, though the likelihood of finding it is generally rather
slim at this point and may not always be worth the effort.

When you're ready, head on over to the boss room and see who the game sends
your way. Your first fight will most likely be with Monstro who can take a
beating but is easy to dodge.
Other possible bosses include Gemini, Larry Jr. and the Duke of Flies.
On a very rare occasion you might face the Fallen instead... if this happens
you should cross your fingers and steel yourself as he is of a much higher
difficulty level. On the bright side, if you do manage to defeat him the reward
is often well worth it!

After finishing off a boss you will always be rewarded with a treasure and a
trapdoor will appear in the room. At random, a second door will appear with a
gargoyle over it, this is the Devil's room. Consider entering if it appears,
but be sure to read the rooms section first!

Your second treasure (from the boss) will more than likely be a health or stat
boosting item. Claim your reward and delve deeper into the basement.

Before you leave, should you have any bombs or keys left, consider visiting the
shop, shearching for the secret room or obtaining any locked chests/blocked
items. Your minimap will conveniently list any left-behind items and chests, so
feel free to manage your inventory at this point.

Dark-tinted rocks (blue-ish in shade) are not there for looks, they are
guaranteed to contain a random item (often soul hearts) when blown away by a

From here things only get harder!

After floor 1, all treasure rooms will be LOCKED, so keep a key handy to open it

Floor 2 will typically offer more of the same as floor 1 with some added
difficulty, size, and slightly more to see than before. Just take this floor
one room at a time keeping on the defensive, no use wasting HP.

In the event of you receiving 2 activated items (one from the first floor,
another on the second), now would be a good time to fully understand what each
one does. Prepare to leave one behind but feel free to use up the second one
before you part with it for good.

This floor will typically have about 13 rooms to explore.
At this point you may encounter a room with bars. This is the arena. See the
rooms section!

As was the case in the previous floor, explore and grab your treasure if you
can. Keep safe and take on the boss at your leisure. Get a hold of the flow of
the game and work on hit and run tactics with any enemies that can spit blood
at you.

Your second boss fight will likely be either Monstro (if you did not kill him
previously), Gemini, the Duke of Flies or Larry Jr.
Claim the second boss' treasure and dive into the next section, the caves!


From here on in you may encounter Pits, Spikes and Explosive Barrels. See
dungeon features for more information.

The caves are larger and more dangerous than the Basement, introducing more
enemies, bigger floors (resulting in a greater variety of rooms), stronger
bosses and harder to reach items.

In addition to the previous enemies you may also now encounter:
-Boom Fly
-Knight (rare)
-Leaper (also rare)
-Mr. Maw (also rare)

As with the Basement, prepare to play defensively and conserve your hearts.

The list of possible bosses for the Caves typically includes Peep, Chub,
Fistula or Gurdy. For the most part, none of them are that difficult if handled

Keep hunting down those treasures and start considering store purchases as you
will likely have plenty of money to spend at this point.

Need more HP? If you encounter a blood bank/blood donation machine (see
rooms/dungeon features) consider donating some HP for cash. If you're lucky you
can score a Blood Bag which will boost your max HP.

You may from this point forward encounter weakened bosses randomly instead of
normal enemies!

Keep safe, fight well and the basements should breeze by.


If you've made it this far, you've either gotten lucky with the right treasure
combinations or have gotten the hang of the game. The Depths will offer more of
what the caves gave you plus more enemies than before including:
-Mr. Maw
-Leech (rare)

Additionally, previous bosses may appear normally instead of enemies, including:
-Fistula (multiple parts but never the whole)
-Blastocyst (occasionally the smallest parts)
-Larry Jr.

In addition to all the dangers of the previous floors, the Depths may also
include Statues which will spit blood at the player until the room is
completed. These CANNOT be moved or destroyed AT ALL.

Door blocks will now occasionally appear, blocking access to chests or features.

Your first floor boss here will either be Loki, Monstro II or a previous boss
at a higher difficulty level.

As you progress, hearts and healing items will become rarer, treasure chest
contents will be less useful, enemies will be stronger and often the random
elements of the game will flat out start trying to kill you. Be conservative at
this point, it doesn't hurt to be overprepared.

The final level of the Depths will mark the closure of your first adventure.
This floor will contain your last shop and treasure room, so be sure to visit
both. If you have money to spend, buy what treasures you can. Prepare for the
boss and ensure you've done everything you need BEFORE entering the boss room
(especially if this is NOT your first play through) as after finishing this
boss you will NOT be allowed to re-enter the depths.

*********POSSIBLE SPOILERS BELOW*****************

The boss here is Mom, check her up in the boss section and be ready for one
crazy fight.

After finishing Mom, you will have beaten the Binding of Isaac if an ONLY if
this is your first time playing it, otherwise you will be given another
trapdoor and be sent on your way to...

*********POSSIBLE SPOILERS BELOW*****************


If you thought the previous floors were hard and or creepy, then you're in for
one crazy surprise because the womb is harder and creepier than before. Bosses
are more common in random rooms, all damage is increased to one heart damage.
Additionally, there are no treasure rooms (save for the possibility of a
treasure in the secret room), no shops and definitely nothing "easy".

NOTE: From here on in, Blood Donation Machines will consume ONE FULL HEART
instead of half a heart. Be extremely cautious if seeking a blood bag.
The monster list now includes:

as well as most of the previous bosses fought including:
-Larry Jr. (in various quantity/length)
-Monstro (in various size/quantity)
-Gemini (sometimes 2)
-The Duke of Flies (rare, sometimes 2)
-Blastocyst (all but the largest, sometimes up to 5)
-Chub (sometimes with other bosses)
-Fistula (including the full boss)

There usually isn't much of a reason to stick around and explore unless you
need to charge up your activated items or are hoping for a random treasure out
of a chest or mini-boss should you find one.

The boss on the first floor here will either be Blastocyst (in his full form)
or Scolex. Neither is too difficult and you can always go back after beating it.

By this time you should be making your final preparations for the final floor
of the womb. These rooms will only get harder, the fights more intense and
naturally this is all leading up to an epic battle against...

*********POSSIBLE SPOILERS BELOW*****************

Mom's Heart! As with the fight with Mom, you will not be able to leave
afterwards, especially if this is your first time fighting it.

Assuming you beat Mom's Heart (easier than it sounds) you will be offered a
giant golden chest. Open it to claim your reward, but be aware that if you
finished with enough HP or have properly unlocked Sheol, you may receive a
Devil's Room in addition to the Chest. In the Devil's Room you will find a
trapdoor leading deeper still... this time to Sheol. Passing up the chest for a
shot at Sheol will NOT cause you to lose your reward OR the resulting ending
clip, both will be unlocked automatically if you choose to go deeper and will
be waiting for you upon your resulting success or failure. NOTE: if you manage
to complete Sheol BEFORE properly unlocking it, it will count DOUBLE towards
your completion count (meaning you will get an extra unlock!)

*********POSSIBLE SPOILERS BELOW*****************

This area was added with an update to the Binding of Isaac and features your
greatest test of courage and strength. Here you will find NO help save for a
possible single arena and a definite secret room. Bosses and mini-bosses in
duplicate forms, with additional enemies and in all varieties can be found here
instead of normal enemies and rewards are virtually nonexistant. Avoid getting
hurt at all costs and be prepared to keep a full healing item on hand if you're
lucky enough to find one. Hearts are scarce and damage is high, nearly all
normal enemies will be improved "champion" varieties (see monsters section).
Additionally the following enemies will also appear:
-Dark Dople
-Evil Eye
-Exploding Leeches

The boss here will ALWAYS be Satan. Defeat him and obtain your ultimate reward
and the final mysterious ending.

CHARACTERS                     |

The Binding of Isaac offers 6 playable characters, each with different starting
items and stats, as well as a slightly different appearance.

Isaac - Starting character
HP - 3
Speed - 2
Tears - 2
Attack - 2
Range - 2
Starts with 1 bomb
*Starts with the D6 once unlocked

Cain - Unlocked by obtaining $0.15 in any one playthrough
HP - 2
Speed - 3
Tears - 2
Attack - 3
Range - 1
Starts with 1 key
Starts with the "Luck Foot"

Madgelene - Unlocked by having 7 or more HP at any time in one playthrough
HP - 4
Speed - 2
Tears - 2
Attack - 2
Range - 2
Starts with the "Yum Heart"

Eve - unlocked by making 2 deals with devil in any one play through
HP - 2
Speed - 3
Tears - 2
Attack - 1
Range - 2
Starts with the "Dead Bird"
Starts with the "Whore of Babylon"

Judas - unlocked by beating the Womb 2's boss
HP - 1
Speed - 2
Tears - 2
Attack - 4
Range - 2
Starts with 3 Pennies
Starts with the "Book of Belial"

??? - unlocked by beating the Womb II 10 times
HP - "-1"
Speed - 2
Tears - 2
Attack - 2
Range - 2
Starts with 3 Soul Hearts
Starts with "The Poop"
Does not Gain HP, all HP+ treasures add soul hearts instead. Cannot heal
naturally with hearts.

ENEMY LIST                     |

Throughout all of the Binding of Isaac you may encounter many types of enemies,
use this guide to be prepared for what the darkness might throw your way!

Flies - Black dot with wings
Have a small amount of HP, normally can be killed in one shot, rarely two.
Deal 1/2 Heart damage on touch
Fly around the room randomly, no set path.
Can turn into pooters in the presence of poo if left alone long enough.

Attack Flies (red) - Flashing red dot with wings
Slightly stronger than normal black flies
Follows the player around the room instead of buzzing about randomly.

Pooters - Black fly with eyes and a large white thorax.
Tends to follow or avoid the player
Will occasionally shoot blood at the player, deals 1/2 heart damage.

Suckers - Black fly with a large stinger and red sac.
Behave like normal attack flies.
On being killed, these flies fire a + shaped pattern of blood shots. Each deals
1/2 heart damage.

Moters - Double sided fly
Behave like normal attack flies.
Splits into two attack flies on death.
Will not spawn attack flies if killed in one hit.

Gaper - Identical to Isaac with bloody tears (smiling), occasionally have their
eyes closed (frowning)
Moderate HP
Will follow the player on a direct route if possible.
Deals 1/2 heart touch damage.
Frowning Gapers will follow the player at greater speeds.
Has a chance to spawn a Pacer or Gusher when killed (greater odds from frowning

Pacer - Headless corpse
Shambles around the room randomly
Deals 1/2 Heart touch damage

Gusher - Blood-spurting Corpse
Shambles around the room randomly spewing blood
Deals 1/2 Heart touch damage
Regularly sends out a single blood shot in a random direction. (1/2 Heart

Hopper - Hopping Corpse
Jumps around the room randomly, will follow the player if they get too close.
Deals 1/2 Heart touch damage.
Can jump over obstacles in the room.
Becomes a Flaming Hopper if it touches fire.

Flaming Hopper - Burning, Hopping Corpse
Has double the normal HP
Always follows the player
Jumps farther and faster

Horf - Floating, Eyeless Head - Stationary
Does not move normally
When the player is within range and clear sight, will fire blood balls at the
player at regular intervals.
Deals 1/2 heart touch and projectile damage.
Can be moved with the normal knockback effedt of tears.

Mulligan - Badly Stung Creature, covered in boils and stings
Flees from the player normally
Does not deal touch damage
On death, spawns 2-4 random flies
Occasionally explodes randomly, launching a + pattern of small projectiles.

Mulligoon - Mulligan with its eyes sewn shut
Behave identically to Mulligans
On death, fires an X pattern of small projectiles and spawns a troll bomb
Occasionally explodes randomly, launching a 6-way pattern of small projectiles.

Clotty - Pile of meat with bone and eyes
Fairly random movement pattern
Regularly fires a + pattern of small projectiles.

Clot (AKA Mini Gish) - Black blob with yellow eyes
Behaves identically to Clotties.
Fires a regular X pattern of small projectiles.

Embryo - Small hopping fetus-like creature
Very low HP
1/2 heart touch damage
Does not follow the player
Usually spawns with other embryos and a mini-boss health gauge between them.

Boom Fly - A bloated Black fly
Bounces off walls in a linear path (diagonal)
1/2 heart touch damage
Explodes when killed, deals 1 heart damage

Bloat Fly - A bloated red-ish fly, similar to Boom Flies
Behaves identically to Boom Flies
Fires a 6-way pattern of projectiles when killed.

Maggot - A white maggot
Blind - it will never follow the player, moves randomly around the room
Deals 1/2 heart touch damage.

Charger - A white maggot with a small face
Behaves identically to maggots.
When in direct line of sight, they will open their mouths and charge at the
player quickly.
Deals 1/2 heart touch damage.

Spity - Bloated Maggot with face and eyes
Behaves identically to maggots.
Randomly fires blood in whatever direction it is facing.

Host - A stationary skull filled with intestines.
When in range of the player, the host will raise up and fire a triangle of 3
projectiles at the  player.
Invulnerable to damage while the skull is down.
Do not deal touch damage.
If dealt enough damage while protected, the Host will grin at the player.

Red Hosts - A host with a fleshy skull (DO NOT confuse this with the occasional
red champion hosts)
Always vulnerable to damage
Fires more frequently
Fires a spread of 5 shots instead of 3.

Hive - A Mulligan full of flies
Behaves identically to Mulligans - Flees from the player.
Occasionally coughs up flies, up to about 3 per hive.
On death, spawns up to 5 flies.
Never explodes randomly.

Maws - Similar to Horf, but with a gaping mouth and slack jaw.
In addition to regularly spitting blood, Maws will attempt to float towards the
player to deal touch damage.

Closed Maws - Red-tinted Maws with the mouth sewn shut.
Cannot fire blood balls at the player.
Increased movement speed.
Fires a + pattern of blood shots when killed.

Leaper- A Hopper with darker skin and a bloody neck.
Has a stronger AI than Hoppers.
Occasionally jumps off-screen and lands near you (shown by a shadow). Fires a +
pattern of blood shots upon landing.

Baby (AKA Sirens) - Floating ghost-like creatures with bloody mouths.
Float around wailing and shrieking, each time firing a blood ball towards you.
Occasionally teleports away and reappears elsewhere in the room, sometimes near

Boil - A small blob of flesh that quickly grows in size.
Does not have normal HP, regenerates in size constantly. Must be reduced to be
When at its full size, it will spew a random wave of blood balls (some small,
some large) towards the player.

Guts - A ball of intestines
Rolls around the room clinging to nearby surfaces.
Has a fixed route.

Brain - A brain-like slug that slides across the floor
Randomly travels across the room.
Leaves a trail of blood across the floor - hurts when touched.

Vis - A fat, headless corpse with an opening in its chest.
Randomly moves around the room. When in line with the player it will shake and
charge to fire a blood beam from its chest. This beam will travel across the
entire room, pass over obstacles and will last a few seconds before

Globin - A skinless corpse made from muscles
Follows the player if able.
When destroyed, is reduced to a pile of meat which will regenerate if not

Hemo-Globin - A Globin with a single eye in its head
Behaves identically to the globin
Slightly more HP
Can flee from the player while reduced to a meat-pile.

Mr. Maw - A maw with a body
When in range, he will send his head flying at you for touch damage.
May randomly split into a Pacer and Maw.
Releases a Maw on death.

Knight - Stone-like corpse with an exposed brain in the back of its head.
Behaves almost identically to classic Darknuts from the Legend of Zelda -
Randomly moves in straight lines, occasionally turning towards the player.
Will speed up slightly when approaching the player.
Can only be injured from the back.

Knight-mare - A Knight with a horrified expression and Isaac's face on the back
of its head.
Identical to Knights with extra HP.
Has a greater chance of turning towards the player.
Will speed up MUCH more when approaching the player.

Membrain - A massive brain
Slides around slowly
Occasionally jumps and fires an 8-way attack
On death, splits into two brains

Leech - A flying parasite
Flies around the room - dashes at you when in clear line of sight

Exploding Leech - A black leech with an eye in its mouth
Has additional HP
Explodes on death

Fred - A strange fetus like creature
Occasionally spews a green glob into the air, explodes on impact with the
Will sometimes jump into the air and dive into the ground, releasing an X
pattern attack. Will resurface elsewhere

Para-Bite - A small worm with a large mouth.
Will slide around the room and follow you for touch damage.
Can dig into the ground and emerge elsewhere in the room.

Lump - A fleshy lump with a face
When in range, will spew a triangular attack at you and dive underground,
resurfacing elsewhere in the room.

Pokies - Spike covered blocks
Slides across the floor, smashing all enemies and its. Cannot be killed, dies
automatically when every enemy in the room is dead.

Eye - A large nerve-covered eye in the room.
Does not move, will spin around until lined up with the player, then will
charge and fire a small laser.

Evil Eye - A clean white eye in the room.
Has additional HP
Tracks player faster.
Charges faster.
Fires a wider blood beam.

Dople - A doppelganger of Isaac made from muscles
Will mirror the players movements and attacks.
Attacks will only be directed to the player if they direct the attack at Dople.
Will scale over terrain and enemies, ignoring anything in its path.

Dark-Dople - A black, flying demon with three red eyes.
Has additional HP
Attacks with a triangular pattern of large blood balls

BOSS LIST                      |

In the Binding of Isaac, bosses fall into a few basic categories:
Normal Boss - Occurs in a boss room at the end of every floor
Mini-Boss - Appears in a mini-boss room, randomly found in floors, shops or
secret rooms.
Champion/Enhanced/Alternate Boss - Replaces a normal boss randomly
Random Encounter - A boss may appear with or in lieu of enemies in a room in
any floor in the Caves or Deeper. Includes most normal, mini and champion
The Basement:
#Monstro# - A large head with a cleft pallet.
Spews a wave of blood, easy to dodge, often miss. Large shots deal 1 heart
damage, small shots deal 1/2.
Jumps around attempting to hit the player for 1/2 heart damage.
Jumps into the air off screen, crashing down and sending blood flying out in
all directions. 1/2 Heart damage, 1 if hit by large shots.

Alterate forms:
Dark/Grey - Increased size and HP, cannot leap off screen

Red - Smaller size, reduced HP, appears in pairs.

Strategy: Monstro, in terms of bosses in the Basement is difficult for a first
boss, especially if this is your first time playing, though overall he's a
pushover if you know what you're doing.
Monstro's attacks are all weak and rarely hit you, but he's a tank, so you'll
have to weigh either a very long or slightly dangerous fight. Your best bet is
to circle him and attack constantly, backing off only when he pauses for an
attack that he will telegraph with plenty of time to avoid. Just play it safe
and he will die, eventually.

#Larry Jr.# - A long, segmented work
Randomly moves around the room, rarely directly attacks the player,
occasionally drops piles of poop blocking your movement.

Alternate Forms:
Green - Reduced HP, can randomly fire blood shots in whatever direction it is
facing for 1/2 heart of damage, easy to dodge.

Blue - Increased HP, larger in size. Will not leave behind poop. He will not
split until he is at low HP. Drops a soul heart when killed.

Strategy: Larry is one of the most common bosses in the game, and is one of the
easiest too. Just keep a distance and take them out one at a time. Larry will
typically spawn with 2 or 3 bodies, each one at a random length. As Larry
weakens, segments will be destroyed and he will be "cut" shorter. A push-over
and easy to avoid and defeat.

#The Duke of Flies# - A large floating head stuffed with flies.
Attacks: Coughs up flies and attack flies, as well as special Large Attack
flies that deal 1 heart of damage.
Can deal contact damage while floating around.
When the number of flies around the Duke reaches its max, he will send the
flies flying towards you with a big push.

Alternate Forms:
Blue - Faster movement

Orange - Faster, spawns attack flies and suckers instead of normal flies and
attack flies.

Green - Spawns Moters instead of normal flies, coughs up a ring of blood every
so often.

Strategy - The Duke is pretty easy as a whole, but can get out of control if
managed wrong. Keep his flies in check, taking out only the ones that attack
you directly. Timing your shots can bypass his fly defenses. Overall he has
incredibly low HP and can sometimes be instantly killed with a bomb if used
properly (practice required). Just play it safe and he'll be easy, if you see
an opening in his defenses, circle around it and focus there.

#Gemini# - A pair of conjoined twins, connected by an umbilical
Gemini is actually 2 seperate bosses, always found together in one battle.
Sometimes one or both can be champion/alt colored.
Gemini Sr. - Will follow you around the room, occasionally charges at you at
high speed after which point he will stop to catch his breath.
Gemini Jr. - Attached to Gemini Sr., will regularly spit blood at Isaac until
he is disconnected or his brother is killed, at which point he will turn red
and fly towards the player to hit them (and will stop spitting)

Alternate Forms:
Blue - unknown effects, +Max HP?

Green - May start the battle detached, Jr. will only become enraged when Sr. is

#Famine# - See the Riders Section

#Steven# - A black Gemini
Unlocked by completing the Basement (chapter 1) 25 times

Very similar to Gemini, though the tether between the two is tiny, so the two
appear to be stuck to each other (a reference to a game by Edmund McMillan,
"Time Fcuk")
Little Steven attacks more frequently.
Boss AI is much more aggressive.
When the boss is reduced to 2/3 of its max HP, Little Steven will seperate and
attack directly instead of spitting blood.
When either Steven is killed, he will explode into a spray of blood in all
directions at high speed.

Steven, despite seeming easy, is far more difficult in that he can be hard to
predict at times. If possible, focus on one Steven at a time, though their
close proximity makes this very difficult. You will more than likely be faced
with both Stevens attacking you, which always results in getting hurt one way
or another. Expect the blood spray when one dies and be ready to get hit or
dodge. Keep your distance and always leave an avenue of escape should Steven
get too close.

Always drops either "Little Steve" or "Steven" items. Unlocks "Little Steve"
when killed.

The Caves:

An enlarged charger, he looks like a massive segmented worm.
Chub, out of all of the bosses in the caves, is probably the easiest. Though he
has a decent amount of HP, Chub is easy to dodge and eady to manage as he's
fairly predictable.
Chub has two basic attacks:
Charge; he will open wide and come dashing towards you. While Chub can slightly
adjust his path on the way, as long as you keep a fair distance from him this
shouldn't be a problem. Furthermore, you can use this to your advantage in two
ways. One, his charge will also hurt enemies in the room, so allow him to
gobble up anything you don't feel like killing yourself. Second, his charge
will also consume any lit bombs in his path. Doing so will stop him and after a
brief pause the bomb will detonate in his stomach dealing normal bomb damage
(also to you if you're too close). As a last resort this not only stops his
charge, but hurts him AND makes him vulnerable to any other bombs you may
decide to lay next to him.
Spawn: Chub can stop and spawn enemies from his backside (yuck). Depending on
Chub's color/variation he can spawn smaller chargers usually to a maximum of
about 3 total in the room. Feel free to let him spawn to the max as this will
cause any future spawning attempts to simply do nothing, leaving Chub

So as for strategy, just lead him around the room, taunt him into attacking and
just play things safe. He should be pretty easy to take care of.

Blue: Chub is slower but bulkier. Additionally he will spawn special Boils
instead of chargers. Deal with the boils first as they can become very
dangerous and difficult to dodge!

Green: Chub will spawn Spitties instead of chargers and will always spawn 2 at
once. There will be a max of 3 Spitties at any one time.

Orange: Chub gets smaller, maybe a bit weaker, but gets a noteable speed boost
and a more erratic AI so he's a lot more difficult to dodge or deal with

"Fixed": This will never appear as a normal boss, though in certain situations
Chub will spawn without his final segment. In these situations he will never
spawn any enemies at all.

A giant ball of flesh and tumor and who knows what else. This monstrosity
floats around the room much like Envy, bouncing off walls and pits for some
reason. This thing has no real attack and will never attack you directly,
though he can become dangerous if you let him get out of hand.
Hurt Fistula enough and he will split into 4 medium parts, each of which will
also split into 2 small parts when hurt enough. As a result Fistula gets faster
and can have up to 8 parts at once. Individual parts can be found in rooms as
early as the Caves.
After killing a small Fistula, the part destroyed will immediately spawn a
Charger which can attack you. Chargers can sometimes take more punishment than
Fistula itself so be careful!

Alternate form:
Dark-Fistula: Darker colored and usually a bit bigger in size. This version
will initially split into 3 instead of 4 making a maximum of 6 total parts at
the end. Each destroyed part will release a Boom Fly or Bloat Fly instead.

Everyone's favorite piss-spraying blob of... disgust. Peep is one of the more
difficult bosses in the caves and can often cause a bit of pain if not taken
seriously or carefully!
Peep slides around and attacks occasionally;
His normal attacks include releasing a puddle of urine which hurts you if you
walk over it for a full heart of damage.
Peep is also able to hop up slightly and, upon landing, will spray out a dense
circle of piss balls, each of which does 1/2 heart of damage.
Finally, Peep can jump off screen Monstro-style and will land wherever the
player was when the attack starts tracking you, so he shouldn't land on you if
you move. Landing will cause him to release another circle spray of urine at
When Peep reaches 66% and 33% HP he will lose one of his eyes which will go
floating out and will now bounce off walls in a bishop-pattern. These will do
touch damage.

Dealing with Peep isn't too hard, but avoiding getting hurt is. His circle
spray is fairly common and will require the player to back off to dodge, so
keeping a constant distance from Peep always helps. Use the room's natural
cover (if there is any) to help avoid attacks and remember that touching his
piss puddle hurts you more than anything else. Once he loses an eye or two keep
in mind that they will block your shots AND hurt you if they get in your way,
so make dodging them your first priority and take your time while playing
things safe.

Alternate forms:
Green: Peep will lose both eyes right off the bat! Now you get to fight this
guy while dodging 24/7.

Yellow: Peep will constantly leave behind a trail of piss that will hurt you,
even while he is jumping around though he is physically smaller in size.

By far one of the harder bosses in the game, and definitely one of my least
favorite. Gurdy is a massive pile of flesh and fat and who knows what else...
with a face. Gurdy stays stationary in the center of the room and typically
starts the battle with a pair of Boils and some flies in the room.
Being immobile, Gurdy makes use of a larger variety of attacks and abilities:
Blood wave: Gurdy will crawl into her body mass and pop out on either the front
or side (depending on where the player is), then immediately spew out a 5-part
spray of blood balls which become rather difficult to dodge.
Spawn flies: Gurdy will spew out attack flies behind her. After some time they
will move towards you.
Spawn Pooters: Gurdy will raise her arm and release a pooter from her armpit!
Spawn boils: Gurdy raises both arms and spawns a pair of boils in front of her.

Gurdy has a ton of HP and takes the longest to kill. All you need to know to
kill her is that you must remain diligent at all times! Kill the boils first
and make them your priotity if they appear. Ignore her other summons if
necessary and never stop shooting. When in danger, laying bombs in front of her
will speed the battle along.

Dark-Gurdy - Bigger, stronger, more HP... she can't spew blood anymore but
spawns far more frequently. Perhaps this version of Gurdy is slightly easier
than normal. Why? Well in this form she still has her spawn limits and the
player can camp the far side of the room and go largely unharmed through the
whole fight. Just don't fall asleep.

See Riders section

C.H.A.D. is a living blob of blood and clots, and an unusually happy one to
C.H.A.D. behaves identically to Chub with a few primary differences:
C.H.A.D. spawns suckers instead of chargers.
He will shrink in size as you hurt him and increase in speed.

C.H.A.D. always drops Little C.H.A.D. when defeated. For an easy fight you get
an ok reward, though he becomes largely useless when you get enough soul hearts.

The Depths:


Another rare boss, you'll typically see Monstro II more often than Loki until
you reach chapter 5 where he *might* appear in doubles.
Normally, Loki is a little red imp who floats about and attacks randomly. Loki
mirrors chaos perfectly in that, at any time there is a lot going on with him.
Loki's room will hav a single floating poky in the room which will be cause for
some wariness on your part. Keep an eye on it.
Loki himself can either:
Teleport elsewhere in the room.
Send an 8 way attack of blood balls at you.
Launch a 4 way + pattern, then a 4 way X pattern then another 4 way + pattern
Or summon a Boom or Bloat fly, which, if a Boom fly, can be used to hurt him

Knowing what Loki will do in advance is impossible, but knowing what he can do
helps. Simply deal with each individual attack one step at a time and you can
finish this battle unscathed.

#Monstro II#

Monstro's back with some improvements this time! Probably one of the easiest
bosses in the game if handled correctly.
Monstro II has a few simple upgrades from Monstro:
His bloody spray us now a blood beam that triggers if the player is in a
horizontal line from Monstro II
Monstro II will always super jump twice consecutively, each time either firing
an 8 way pattern of large blood balls or spawning 4 suckers.

Killing Monstro II the easy way!
Simply stand directly across from the beast and let him prepare his blood beam
which he will telegraph with a smile. When he does, strafe in a semicricle
around him attacking on the way and stopping directly in range of his blood
beam, BEHIND him. If done properly, Monstro will turn around and prepare to
roast you with another blood beam. Lather, rinse and repeat and you can come
through without even a scratch. Should he instead decide to super jump, just
dodge, kill any enemies spawned and get back to provoking him again.

Overall Monstro II is rather rare since there is only one boss in the Depths
besides the guaranteed one (see below) and his alternates are even rarer.
For the most part, one form will cause him to spawn less but move more, another
will make him more buff overall, though the same strategy applies either way.

See the riders section


It's time to face your fears and confront MOM!!!
Now is your first real milestone, and completing this boss will unlock the rest
of the game.

Mom's room is special, it has randomly scattered rocks and 4 boss room doors in
each of the cardinal directions.
The fight begins with Mom's Foot crashing down in an attempt to crush you,
dodge this.
From here on out, Mom has 4 parts/forms that will appear randomly all at once.

Mom's Foot: Will occasionally track you (a shadow will appear) and stomp down
on the ground, creating a bomb explosion, destroying rocks, enemies and
anything else in its wake.

Mom's Eye: Pops out of a door, it is defenseless so attack it to hurt Mom more!

Mom's Flesh: Pops out of a random door, spawns an enemy to defend itself and
eventually disappears. Hurt it like Mom's eye, but keep a tab on the enemies it
spawns, you'll need to take them out to keep alive.

Mom's Hand: If you stand too close to a door, open or closed, Mom's hand may
quickly pop out to smack you. Keep a distance from the doors to avoid this!

To make this battle predictable would be impossible, but to make it easier is.
For starters, Mom will telegraph her foot stomp with a grunt, so let the foot
land where it will do some good, such as on rocks or enemies. As for whatever
the flesh spawns, know that there is a total spawn limit, but you'll want to
control anything that will shoot at or chase after you, ESPECIALLY Globins.
When an eye appears, attack it. When the leg appears, attack it. When a peice
of flesh is exposed, attack it. Don't miss any easy opportunities and be
careful if you can. If this is your first time, be more concerned with making
sure Mom dies before you do, if you have unlocked the ability to go deeper, try
and preserve your hearts if possible.


Gish is a replacement for Monstro II once unlocked. He resembles a massive
black glob of tar and fights accordingly.
Gish behaves identically to Monstro/Monstro II.
He spews out a black tar bomb that explodes on impact. This leaves behind a
trail of tar that slows you if you walk through it (thats all the tar does,
it's safe to touch)
Gish's super leap is identical to Monstro II, being two leaps successively. The
first one does nothing, the second will spawn two Mini-Gish enemies.

Otherwise, Gish is probably almost as easy as Monstro II save for the fact that
the Mini Gish enemies spawned can occasionally be a hassle and his AI is not as
easy to manipulate, but he's rather harmless for the most part.
Killing him nets you the Little Gish familiar.

Chapter 4 - The Womb:

Scolex is the weakest boss in the Binding of Isaac. He has the least HP of any
boss and can sometimes be instakilled if hit with a bomb or a powerful attack.
Scolex is a large tapeworm and has a weakspot on his tail. Hitting him
elsewhere will do nothing.
Scolex will leap in and out of the room a few times, after which point he will
either stick out his head or tail (ATTACK!) and then dive back in again. His
head will spew out three blood bombs that will explode on contact with the
ground, his tail will spew a random cloud of blood balls.

Just hit his tail with good timing and you'll be done in no time at all!

Blastocyst, unlick Scolex, can actually be hard at times.
This fellow is a single "Embryo" enemy (you'll have seen a few of them by now
at this point) within a blob of jelly.
He will bounce around a lot, spraying random bits of blood around and
occasionally will fire out an 8 way pattern of blood.
Killing him will cause him to split into 2 medium parts which will no longer
spray blood but can still fire 4 way X or + patterns of blood. Each of these
will split into 2 small parts when hurt, which can now only spray + patterns of
Finally, killing the smallest part yields a single embryo which can do...
nothing. Just kill it.

To deal with this uncommon fellow, just break him down to his second form as
quick as possible, then again into his third form. Doing so eliminates his
ability to attack diagonally which makes dodging all the easier. If you only
manage one at a time, the remaining half can still attack on diagonals so your
ability to work out a safe spot in the room is hampered a bit. If there are 4
small versions, however, you typically can work out an area in which you can
predict who will attack where and dodge accordingly, leaving that nice little
safe haven, often in the middle of the room, where you can catch your breath
and pick them off one by one.

See the riders section

#Mom's Heart#

This is it! Another major milestone for you and Isaac!
Mom's Heart, unlike Mom herself, is a stationary boss. Killing it is likely
EASIER than killing Mom at times. At the start of the battle, Mom's Heart will
be flanked by two eyes. Take these out first. No exceptions.
Mom's Heart has a predictable behavior: If there are enemies with it, the Heart
will rise offscreen and hide. If there are no more enemies with the Heart, the
Heart will descend and summon more. After a few seconds, the heart will rise
away again.
Once all of the enemies spawned are killed, the Heart will return and summon
more. This can continue forever if you don't focus on the Heart while it is
vulnerable. When the Heart is down, concentrate on it! Hurt it as much as you
can, THEN kill its minions.
Once the Heart is down to about 33% of it's HP, Mom will scream out Isaac's
name erratically (you'll know it when you hear it) and from this point forward
the battle gets a bit more intense. Instead of hiding, the Heart will now stay
down and summon enemies, all the while sending blood bombs flying in random
directions, exploding and leaving blood pools. These can hurt enemies too, but
don't count on it. Just kill the Heart as quickly as possible to avoid getting
too hurt.

At this point, you shouldn't need too much more advice, just kill the heart and
if you have all your heart containers full, be ready to have the chance to go

#It Lives!#
Once unlocked (after beating the Heart/Satan a cumulative total of 9 times) you
will unlock It Lives! It Lives will now ALWAYS replace Mom's Heart and simply
ups the difficulty by spawning bosses instead of normal enemies.
The only difference between Mom's Heart and It Lives is the difficulty of the
enemies (bosses and knights and such) which get spawned. Otherwise, the only
difference is aesthetic and that much I won't spoil for you.

Chapter 5 - Sheol:


This is it! The final battle! Satan is ready to punish Isaac for his sins and
boy is he going to put up a fight.
This battle consists of 3 phases and I highly recommend you stock up on HP
before you fight him if possible. Lastly, if by some rare chance you're
carrying the Bible item, use it BEFORE even entering the room as using it in
front of Satan at ANY time will instantly kill you.

Part 1:
Satan will summon the Fallen flanked by two exploding leeches. Focus on the
leeches first as they can hurt the Fallen if detonated properly. A well timed
bomb before these minions appear can wipe out both leeches and put a dent in
the Fallen though this is difficult to pull off.
See the Fallen's section for more info on him, there's no other twist here
besides the 2 leeches and the natural Full Heart damage pentalty in the level.

Part 2:
Clearing out Satan's minions will cause the fallen angel himself to face Isaac.
Satan will rise from his pedastal and transform into a massive demon.
Satan's first form will hug the back wall and will travel back and forth with
no real pattern. He will frequently cough up two consecutive fans of large
blood balls, which obviously do 1 damage each. The fans will always be pointed
directly at you and are densest when first fired. Strafing is always an option
but Satan has a problem with that too. Passing in front of Satan may trigger a
very quick attack in which he will either spew a blood beam from his mouth or
fire two beams from his hands (leaving room in the middle). Thr reaction time
required to dodge either attack is VERY quick so avoid passing in front of
Satan and additionally try not to stop there when doing so!
This battle doesn't change at all for the entire duration, so play things safe
and chip his HP to 0.

Part 3:
When Satan his 0 HP he will fall to the ground, but the get back up and leap
offscreen, laughing.
Now comes the most chaotic part. Play this by ear and avoid getting hurt too
much, but balance this with the fact that you want to get done ASAP!
This is the VERY end so be prepared to come within an inch of your life.
In this new form Satan, from his invisible perch above, will send his massive
feet crushing down on you in an attempt to crush you just like in your battle
with Mom. The feet will display a shadow before falling, will land and release
an explosion (splash damage will happen!). The legs will come crashing down one
after the other, raising up to come crashing down again. All the while, Satan
will constantly summon Exploding Leeches (up to 2 at a time) which can cause
plenty of trouble if you aren't careful since you usually don't see them spawn.
I cannot tell you what weapons you'll have, nor how you should approach this
battle (offensive or defensive) but at this point use your best judgement and
remember, at this point you either win or lose.

The Riders and other Bosses:

Famine is the starved out horseman of the Basement. He can replace any boss in
the basement once unlocked.
Like all riders, he has 2 phases and in each phase has different attacks.
In his normal form, Famine will either spawn pooters (up to 2 at a time) or, if
the player is within his direct horizontal line of sight, he will telegraph a
charge attack where he will charge at you, head offscreen and return on the
opposite side.

His second form will cause Famine to but cut down to only his head, at which
point he will float lazily around and cough up fans of 3 blood balls
periodically, aimed at the player.

General strategy: In his first form, Famine is easiest in that you can provoke
him to attack by charging, which will destroy any pooters he hits and will also
prevent him from spawning more pooters in the meanwhile. Keep him charging and
you can chip him down to his second form without a scratch! In his second form,
do whatever you want, just avoid getting hit when he does attack (which gives
you reasonable time to dodge).
Your reward is your first Cube of Meat.

Pestilence is the rider of the caves. He will float around on his horse and
summon chargers and spitties below him. Pestilence leaves a trail of sickly
slime which will hurt you if touched. His final attack is a ball of goo which
he lobs at you and which explodes on contact with the ground, leaving more
slime and hurting anything in its blast radius (enemies included, though not
the rider himself).

When he is hurt enough, he will lose his head, at which point his horse will
cough up flies and he will continue firing goo balls at you.

Not too difficult really, a relaxing break in comparison to, say, Gurdy.
Pestilence can be dealt with by simply ignoring the enemies he spawns and
instead paying more attention to his goo trails and lobbed goo grenades. Allow
Pestilence to take care of his own minions! When his head comes off, he's
nearly dead, though the flies that get coughed up can annoyingly block your
shots. At this point you shouldn't have any difficulty claiming your next cube
of meat.

War is the rider of the Depths
While War is rather hard to encounter, he is not too hard to fight, though most
certainly isn't as easy as Monstro II.
War's normal attacks are generally harder to dodge, though taking him to his
second form will eliminate all of that danger.
On his horse, War can:
Fire a circular spray of fast moving blood balls (hard to dodge!)
Fly into the air offscreen and release 6 troll bombs throughout the room
When provoked into a charge, War will attack horizontally once, then again
about 1/2 a room lower and again 1/2 a room lower until he finally returns to
his original starting position (the result is 3 consecutive nonstop charges
from the top to the middle to the bottom, or the middle to the bottom to the
top or the bottom to the top to the middle depending on where he starts).

When War takes enough damage, he will lose his horse and chase you Lust style,
in which form he is a pushover. Hurting him enough will trip him briefly.

Not too hard, just watch out for his charges and definitely be prepared for an
unexpected attack.
Killing him nets another Cube of Meat

The final rider! Death appears in Chaper 4: the Womb!
Death can summon scythes to attack you from across the room, either in a pair,
which will track you, or a quartet which will travel across the room. These can
be shot down if needed. Additionally, Death may unleash his Hourglass which
will slow you and your attacks down, making dodging tougher.
Once wounded to about 50% HP, Death will dismount his horse which will enter a
charging pattern like War, but will continue nonstop until destroyed (necessary
to finish the battle!)
Death will now summon knights in pairs (and occasionally knightmares in the
place of a knight) which will behave normally once summoned. Taking out Death
or his horse will still leave the other to deal with.

To fight off Death, try to simply avoid his scythes, attacking only those that
will hurt you and focusing more on Death himself. Chopping him down to his
final form will force you to take out both him and his horse individually, so I
recommend you focus on Death first. His charing horse can and will hurt knights
spawned in the meantime, so just pay attention to where enemies are moving.
Killing Death and his knights only leaves the horse which will continue
charging until you kill it. It has a bit of HP so don't underestimate it.
Death will present you with your final cube of meat.

*The Headless Horseman*
The Headless Horseman is a special boss, like the Fallen and can replace ANY
rider when one is encountered (the Rider will be rolled for first when you
enter the boss room, and if a rider is to be fought then the game will roll
again to see if the rider is replaced).
This means the HH can appear in the Basement 1!
Unlike the riders, HH has both forms at once and is actually a fight against
two bosses at once (both parts can be found in Sheol when you get there,
sometimes in multiples!)

The body behaves a lot like the second form of Pestilence, coughing up blood
balls that leave behind damaging pools of blood.
The head behaves like a cross between War and Famine and will float around,
coughing up a fan of 3 blood balls, as well as occasionally performing War's
3-run charge.

I recommend taking out the body first if you can, especially if the head is
busy charging. Killing the body prevents the room from getting bogged down with
blood. Once he's out, kill the head, watching out for the blood he spews at you.
Killing the HH will either yield "a Pony" or sometimes a normal Cube of Meat.
The Pony is well worth the dangers if you get it early!

/The Fallen\

This dark angel can appear in any boss room on ANY floor and in the basement,
like the Headless Horseman, can be a game ender easily!
The Fallen flies around the room and will spit two successive fans of blood
balls (first 3 then 4). The Fallen will also occasionally stop firing and
charge at you like Gemini, after which point, instead of taking a breather, he
will stop and release a + pattern of blood beams.

At 50% HP the Fallen gets tougher as he splits into 2 smaller versions of
himself who behave identically. Take them out one at a time if possible.
Circle strafing is recommended for this guy, but his blood beam attack will
force the player to take cover in a safe place.

This tough fellow will always reward an item from the Devil's Room list, for
FREE! Rerolling this item will always yield another Devils room item as well.
Worth the trouble if you can survive.

Krampus randomly appears in the Devil's Room upon entering INSTEAD of Satan
with two special sales.
At first glance, Krampus behaves identically to the Fallen with a few minor
Krampus fires an extra blood ball per fan attack.
Krampus will never chase you, nor will he split when hurt.
Standing in a straight line with Krampus may prompt him to fire off a + pattern
of blood beams.

Dealing with Krampus is a bit more difficult than the Fallen in some ways in
that his particular form of attacks is designed to prevent you from circle
strafing. That being the case, you can still circle him, but doing so will
require more care, as damage from the blood beams can take you down if you are
too careless.

Killing Krampus yields the Lump of Coal! This item will make fighting quite a
bit easier for the battles to come.

Mini Bosses, the Seven Deadly Sins:
These appear in mini-boss rooms which are normally unmarked on the map until
entered. Having the compass or spelunker helm will identify them.

Probably the most annoying of the sins, especially if encountered in pairs in
later areas. His rewards are scant and his risk of hurting you is high.
Envy floats around the room like a Blast fly/Fistula. Dealing enough damage
will cause him to split into 2 copies of his head. Killing those will spawn 2
medium heads each. Each of those will spawn 2 miniature heads each when killed.
Each successive head size moves faster and is harder to hit making the room
rather chaotic if you don't focus well enough.
Killing Envy will reward a Troll Bomb, or if you're lucky, Shoop-da-Whoop.

One of the easier sins, he will walk around randomly and either attack by
raging and shooting strange lasers in each of the 4 diagonals. At other times,
he will jump up, put on his Troll Face, and drop 6 troll bombs in random
locations in the room. Pay close attention to the bombs and keep out of his
range/attack spread and he will die pretty fast.
Rewards a Troll Bomb, Tarot Card or the Anarchist's Cookbook

Pretty easy, though he can be painful, Wrath is a carbon copy of Bomberman in
many ways. He will send bombs sliding at you which will eventually explode and
hurt whatever is in his path. Wrath's room is always a specially designed room
with a Bomberman grid and randomly placed rocks.
Wrath can only do blast and touch damage, plus his own bombs can hurt him.
Since touching his bombs doesn't use you, you can push or launch them back.
Killing him will reward bombs, troll bombs, Mr. Boom, or Mr. Mega.
NOTE: Having Bobby-Bomb will make Wrath's bombs turn back towards him.

Definitely one of the more annoying sins, though your trouble is often worth it.
Greed can either be found in shops or secret rooms instead of what you want
(treasure) and appears more frequently if you are carrying more cash with you.
Greed rarely gives any warning to when or how he will attack so either take him
out fast or be VERY careful.
Greed can either fire a quick attack of 3 blood balls in a triangle pattern
(hard to dodge!) or summon a pair of hoppers to assist him. Getting hit by
Greed's attack will cause you to drop coins and lose a coin off of whatever you
had total, so a net loss always occurs if he hurts you.
Defeating Greed grants you a pile of coins or the coveted Steam Sale.

Lust will come out sprinting. She can only chase you down like Gemini but she
won't stop for anything but the knockback of your tears. Slower moving
characters will get beaten down fast if they aren't careful as Lust always
deals a full heart of damage at all times. KEEP MOVING!
Killing lust will sometimes reward a pill, the Virus (cooties?) or Roid Rage.

A rather slow and lazy fellow, he'll either spit chargers at you or cough up
exploding goo blobs. Sloth's attacks often kill off his minions, and he has a
limit of how many he can spawn, so just play it safe and he'll die pretty fast.
Sloth will usually drop a Tarot Card or, rarely, Bob's Rotten Head.

A fat little man with a big body... He will either quicky fire out a large
circle of blood balls (hard to dodge) or fire off his signature Blood Beam
(which he will telegraph in advance). Gluttony's room typically has a gaping
pit in the center, so use it to get some distance between you and him. Be
patient and he shouldn't hurt you too much.
Killing Gluttony yields hearts and sometimes (rarely) <3, the Bucket of Lard,
or the Raw Liver.

ROOM LIST                      |
Empty Room: Multiple variations exist, common types include
Burning Pentagram - Many fires in a pentagram formation
Spike/Pit Maze - often has an item in the center
Beggar/Slot Machine - usually blocked by rocks or keystones
Bomb Maze - Surrounded by breakable and unbreakable rocks with bombs strewn
throughout the room
Stone Circle - A circle of stones with item(s) inside
Cash Corner - Each corner of the room contains coins blocked off by stones

Enemy Room: MANY variations exist, locks when you enter, contains normal
enemies or in deeper levels bosses and mini bosses. Can be bombed out of,
unmarked on map.

Aracde: Marked by a Dice on the Map. Always contains a Slot Machine, Shell Game
and Blood Donation Machine between which a "racket" can be performed by using
the machines to fuel one another and obtain more items/hearts. May contain a
random item/pickup

Treasure Room: Locked below Basement 1, contains a single random treasure.
Marked by a crown.

Boss Room: At the end of every level, contains a boss. When finished a treasure
and trapdoor will appear, as well as a door to the Devil Room sometimes.

Shop: Always locked, contains a random number (2-5) of items and treasures for
fixed prices, sometimes randomly on sale.
Price guide - Price (sale)
Treausure - 15 (7)
Bomb - 5 (3)
Key - 5 (3)
Soul Heart - 5 (3)
Heart - 3 (2)
Tarot Card - 5 (3)
Pill - 5 (3)
Shops may contain the sin Greed, whose appearance rate varies with the amount
of cash the player has.

Blood Bank - Contains a blood donation room and a random number of Embryo
enemies (with a mini boss HP bar)

Devil Room - Appears after defeating the boss, is rerolled if you leave (may
reappear or disappear), contains a Satan Statue and 2 random treasures chosen
from a list of items. These can be purchased for a number of heart containers
of soul hearts. May randomly contain Krampus. If reached on the Womb 2, this
will contain a trapdoor to Sheol. (Items include: The Mark, The Pact, Lord of
the Pit, Dead Cat, Sister Maggy, Brother Bobby, Technology, Lucky Foot, The
Nail, We Need to Go Deeper, Book of Sin, Book of Belial, Book of Shadows,
Common Cold, Necronomicron, Quarter, Money=Power, Yum Heart, Brimstone, Monster
Manual, The Parasite, Ouija, Whore of Babylon, The Razor, Mom's Knife, Demon
Baby, Forget Me Now, Doctor's Remote) Items may cost 1-2 Hearts or 3 Soul
The Devil Room may occasionally contain the Boss Krampus instead.

Challenge Room/Arena/Mob Trap Room (depending on what you call it) - Marked by
crosse swords, contains a random treasure or chest, picking it up or opening it
will trigger enemies to appear in 3 waves before being allowed to leave. NOTE
if an achievement is unlocked by obtaining the item/treasure in the Arena or if
you immediately pause after claiming the reward, ALL THREE WAVES WILL SPAWN AT
ONCE, beware! Waves spawned vary from floor to floor. Unlocks when the player
is at/near their full HP (soul hearts ignored). Also appears in Sheol.
Sheol/Womb contains 3 waves of bosses.

Mini-Boss Room - Can randomly replace shops/secret rooms (see Greed) or on its
own containing any of the other 7 Deadly Sins. Cannot be bombed out of.

Secret Room - Not marked on map, must be bombed into. Typically adjacent to 2-4
other rooms, most often with the Treasure room bordering it. Contains either
Greed, a number of coins or a random Treasure from a list of treasures. (List
includes: 1UP, Bob's Rotten Head, My Little Unicorn, Book of Belial, Raw Liver,
Spider's Bite, Transcendence, Teleport!, and We Need to Go Deeper)

I AM ERROR Room - When teleporting, there is a 5-10% chance of landing in this
room. The room is typically very random/strange and may contain any number of
coins, pills, items and usually all around good stuff surrounding a man in the
room saying "I AM ERROR". Includes a trapdoor to the next floor. A truly lucky
find indeed!
Known layouts include:
2 Free Treasures
1 Free Treasure and 9 Pills
1 Free Treasure, 13 random coins and 3 Shop items/treasures
1 Free Treasure and 4 Chests

DUNGEON FEATURES               |

Pits - Can be crossed only with flight/the ladder. Will not hurt you/cannot
fall in.

Spikes - Hurts when crossing, damage varies from 1/2 to 1 full heart depending
on depth.

Chests - Opens when touched, releases items and sometimes other chests.

Golden Chests - Must be unlocked with a key, typically contains more items and
sometimes a treasure.

Rocks - Blocks your path, can be blown up with a bomb, or blown into adjacent
pits to fill them.

Black Rocks - Cannot be destroyed

Magic Rocks- Blue tinted with an X in the upper right corner. Identical to
normal rocks in the Womb. Destroying these will release coins, bombs, soul
hearts, chests or sometimes the Small Rock treasure.

Keystones - Blocks your path, can be unlocked with a key.

Sentry Statues - Indestructable! Will periodically fire blood at you. Blocks
path even when flying.

Slot Machine - For the cost of one coin, the machine will randomly roll. A
success will result in a reward:
Coin: Drops a few coins
Fly: Spawns a fly or grants a pretty fly
Pill: Grants a free pill
Heart: Releases hearts/soul hearts
Key: Releases key(s)
Bomb: Releases bomb(s) or troll bombs
???: The machine may randomly explode (deals no damage but pushes you back) and
give free items.
Dollar: The machine will explode, releasing the all coveted DOLLAR! $$$ maxes
out cash!
Can be destroyed with a bomb for random items.

Beggar: Giving him a coin will make him happy. Give him more coins and he may
give you free items... and sometimes treasures. Can be killed with a bomb,
doing so usually gives some random items and raises the odds of finding a Devil
Room on completion of the floor. A Treasure rewarded will cause the Beggar to

Shell Game: Giving him a coin will place a random reward into the shell on the
far right (coin, heart, key, bomb, skatole), which will be shuffled around to a
random location. Revealing a shell will have a 33% chance of rewarding the
player with the prize shown (50% with Lucky Foot). The Skatole prize will cause
the Vendor to leave. Can be killed in a manner identical to the Beggar.

Blood Donation Machine: Donating 1/2 of a heart (1 heart in the Womb/Sheol)
will cause the machine to reward 1 or more coins (sometimes 6 or more if very
lucky). Repeated use of the machine raises the odds of the machine exploding
upon use, which will release the rare Blood Bag, which will heal you, increase
your max HP and boost your speed. Bombs can destroy this machine.

Pedastal - Holds a treasure, can be pushed around but will return to its
original position.

Trapdoor - Leads to the next floor!

ITEM LIST                      |

Common items:

Half Heart - Restores 1/2 a heart HP.

Full Heart - Restores a full heart of HP.

Soul Heart - Adds a soul heart to your HP bar. Acts as armor, disappears when

Key - Unlocks a door, chest, or keystone.

Bomb - Adds 1 bomb to your supply.

1 +1 Free - Adds 2 bombs to your supply.

"Troll Bomb" - Cannot be picked up, automatically detonates after a few seconds.

Penny - Adds 1 coin to your wallet.

Nickel - Adds 5 coins to your wallet.

Tarot Card - Grants a random Tarot card to your consumable (Q) slot. (see pills)

Pill - Gives the player 1 pill of the variety picked up (see pills)

Treasure - Grants the player a passive effect.

Activatable Treasure - Grants the player an activatable item to their item
(SPACE) slot.

Familiar Treasure - Grants the player a familiar/orbital

TREASURE GUIDE                 |

These items go into your SPACE slot.
You can only carry one at a time so choosing wisely is important!
After being used, the item must "recharge" its 6 bars over the course of a set
number of rooms (0, 1, 2, 3, 4, or 6).
If an item recharges in X rooms, it gives Y bars per room:
0 - N/A
1 - 6
2 - 3
3 - 2
4 - 1, 2, 2, 1
6 - 1

An item with 0 recharge time can be used immediately after its effect is
finished to an unlimited total per room.

*Anarchist Cookbook - A white book with the anarchy A on the cover.
Randomly generates 6 troll bombs in the room.
3 Room Recharge
-Occasionally dropped by Pride

*The Bean - A small brown bean
Releases a cloud of gas around the player that damages and poisons all enemies
in range.
1 Room Recharge
-Unlocked after destroying 50 poop piles.

*Bob's Rotten Head - A green, eyeless head
Holds the Head over the player, replaces next attack.
Thrown in a chosen direction, explodes on impact dealing blast damage and
poisoning the enemies.
Can hurt the player.
3 Room Reacharge

*The Bible - A light brown book with a black cross on the cover
Grants the player angel wings for the room.
Instantly kills the final bosses of the Depths and the Womb.
Instantly kills the player if used against the final boss in Sheol.
Appears more frequently once the Rosary is picked up.
6 Room Recharge

*The Book of Belial - A black book with a pentagram on the cover.
Removes the players eyes and increases/multiplies attack power for the room.
3 Room Recharge
-Unlocked by finishing chapter 4
-Judas Starts with this item

*The Book of Revelations - A Dark brown book with a white cross on the cover.
Adds 1 soul heart to the player's HP
When used, increases the chances that the level's boss will be a rider.
6 Room Recharge
-Unlocked By Defeating any Rider.
-Commonly found in shops

*Book of Shadows - A light tan book with a strange symbol on the cover.
Shields the player from all damage for a short period of time by granting a
shield. The shield will flicker before it disappears.
3 Room Recharge

*The Book of Sin - A black book with a bloody 7 on the cover.
Spawns a random pick-up (Hearts, keys, coins or bombs)
4 Room Recharge
-Unlocked by defeating each of the Seven Deadly Sins at least once.

*Monster Manual - A small AD&D monster manual
Grants the player a random orbital or familiar for the duration of the room.
Can summon familiars that have not been unlocked.
4 Room Recharge.
-Unlocked by completing chapter 5 with Judas.

*The Necronomicron - A brown book with a face on the cover.
Damages all enemies in the room heavily.
6 Room Recharge.
-Unlocked after using the "Death" Tarot 4 times.

*Dead Sea Scrolls - A tan scroll with black markings.
Randomly duplicates another treasure.
If an activated item is duplicated, the ability activates instantly.
If the item duplicated has a 0-room recharge, the scrolls will recharge
If the item is duplicated is a passive item, it will remain permanently.
Can duplicate items that have not been unlocked.
4 Room Recharge.

*Deck of Cards - A Brown box with an adjacent tarot card.
Grants a random tarot card (any previous consumable item will fall to the
player's feet)
6 Room Recharge

*The Dice (Aka "the D6!") - A red dice
"Re-rolls" all treasures in the room, replacing them with new random-generated
If the treasure re-rolled was not randomly generated (ie cube of meat or
boss-specific treasures) or was generated from a specific list (ie Satan's
items) the re-rolled items will retain the same randomization properties.
3 Room Recharge
-Unlocked by completing chapter 4 with ???
-Isaac starts the game with this item once unlocked.

*Doctor's Remote - A black box with a button and antenna
Summons a crosshair which can be adjusted with the arrow keys.
Drops a bomb on the crosshair after a short delay.
3 Room Recharge

*Teleport! - A blue box with a button and antenna
Randomly teleports the player to another room.
2 Room Recharge

*Forget Me Now - A white tablet
Ends the level, returns the player to the starting room and randomly
re-generates the entire level over again.
Consumed with use.
Unlocked by completing chapter 5 with ???

*The GameKid - A small portable game system (guess which)
Turns the player into a "pac-man" like creature.
Grants 5 seconds of invulnerability.
Deals touch damage to all enemies.
Each enemy killed restores 1/2 heart.
Enemies turn a shade of blue and flee from the player.
6 Room Recharge.
Unlocked by visiting 10 arcades across any number of playthroughs.

*The Hourglass - A small hourglass
Slows enemies and their projectiles for about 7-8 seconds.
2 Room Recharge.

*Kamikaze! - A Bundle of dynamite with a clock attatched
Consumes 1 Heart to generate and explosion at the player's feet.
The player wears the item around his body while carried.
0 Room Recharge.

*Lemon Mishap - A Lemon
Causes a "lemon mishap" at the player's feet, generating a small puddle that
damages all enemies who touch it.
2 Room Recharge.

*Mom's Bottle of Pills - A Prescription Pill Bottle
Grants the player a random pill (any previous consumable item will fall to the
player's feet)
6 Room Recharge
-Unlocked by using Blood Donation Machines 20 times

*Mom's Bra - A large bra
Wears the bra and petrifies all enemies in the room for 5 seconds.
3 Room Recharge.

*Mom's Pad - A woman's pad
Causes enemies to flee from the player while in use.
3 Room Recharge.

*Monstro's Tooth - A bloody bicuspid
Monstro falls from the sky and crushes an enemy dealing massive damage.
3 Room Recharge.
-Unlocked by beating every one of the normal bosses in the basement at least
once across any number of playthroughs.
-Cannot be used against Monstro or if Monstro is present in the room.

*Mr. Boom - A small smiling bomb
Drops a large "Mr. Boom" bomb which can destroy doors and has a larger blast
2 Room Recharge.

*My Little Unicorn - A white unicorn horn
Gives the player a unicorn horn and temporary invulnerability. Deals touch
damage to all enemies when in use.
Cannot attack normally while in use (exception: Mom's Knife)
6 Room Recharge.

*The Nail - A bloody metal spike
When used, turns the player into a demon with twisted horns.
When used:
Grants 1 soul heart.
Increases attack power by 1.
Decreases speed by 1.
Walking over rocks destroys them.
Can break down the arena doors.
6 Room Recharge.
-Can only be found in Satan's Room or by defeating the Fallen.
-Unlocked by completing the chapter 4 3 times.

*A Pony - A Black Horse Head
While carried, the player rides a hobby-horse like the Headless Horseman.
Grants passive flight over obstacles.
When used, will charge in the direction of the next movement, granting
temporary invulnerability and damaging enemies hit.
6 Room Recharge.
Frequently dropped by the Headless Horseman

*The Poop - A Brown pile
Drops a Poop pile next to the player - identical to those found in the basement.
Has a small chance of containing a pick-up item when destroyed.
Blocks enemy movement.
1 Room Recharge.
-Unlocked with ??? after completing chapter 4 10 times
-??? Starts with this item.

*Razor Blade - A silver Razor Blade
Deals damage to the player and grants a temporary attack boost for the room.
Effect stacks
Deals 1/2 heart of damage.
Damage increased to 1 heart in the Depths, 2 in the Womb or deeper.
0 Room Recharge
-Unlocked by completing chapter 4 with Eve.

*The Pinking Shears - A pair of clippers
Separates the player's head and body.
Grants flight while in use.
The player's body will act as a familiar for the remainder of the room,
attacking and dealing touch damage to enemies in the room.
6 Room Recharge
-Unlocked after dying 100 times.

*Shoop Da Whoop! - The iconic face.
When used, grants the player the "Chargin' Mah Lazor" Face.
Next attack fires a delayed lazor which deals heavy damage to everything in its
3 Room Recharge.
-Occasionally dropped by Envy

*Tammy's Head - A cat's head.
When used, fires a 10 way pattern of shots that retain most of the player's
attack-modifying abilities.

*We Need to Go Deeper - A shovel
Spawns a trapdoor to the next level.
NULLIFIES the 0-damage achievements for the level if used to skip the 2nd Floor
of a level.
6 Room Recharge.

*Yum Heart - A red heart missing a bit-out chunk.
Restores 1 full heart of HP
4 Room Recharge
-Unlocked with Madgeline
-Madgeline Starts with this item.

Once picked up these items permantently alter a stat or ability with the
player. Some passive treasures override each other, some have positive
interactions, some have negative interactions.

<3 - A red heart
Adds a beating heart to Isaac's Chin
+1 Max HP
Restores player to full HP

9 Volt - a 9V battery
Adds a bloody batter jammed into Isaac's skull
Activated items are reduced to 2 bars out of 6 when used instead of 0.
Recharges an item carried when picked up
Commonly found in shops

Battery - Large battery with a bolt on it
Adds Electrodes to Isaac's neck
Recharges 1 bar of item power every 20 seconds in a room with enemies, up to 3
bars per room.

The Belt
Gives Isaac a belt around his waist
+2 Speed

Blood Bag
Stains Isaac's face and mouth with blood
+1 Max HP
+1 Speed
Heals 4 HP when picked up
Given as a final reward from Blood Donation Machines

Blood of the Martyr - A thorn crown
Grants a crown of thorns above Isaac's head
+2 Damage
Turns tears to blood

Bobby Bomb - A small bomb with feet and a crank
Bombs dropped or fired will slowly slide towards enemies
Grants 5 bombs when picked up

BOOM! - A large bomb with an x10
Puts a lit fuse on Isaac's head
Grants 10 bombs when picked up

Breakfast - spoiled milk
+1 Max HP

Brimstone - A black and red arcane symbol
Turns the player into a black demon with horns
Replaces normal attack with a charge.
No knockback effect
When fully charged, fires a blood beam that covers the entire length of the
room, dealing heavy damage to all enemies.
When combined with Chocolate Milk, Brimstone can be fired rapidly but deals far
less damage.
Overrides all attacks other than Mom's Knife
Damage increase will increase beam damage, Tears increase will shorten charge
Dropped by the Fallen and found in Devil Rooms

Bucket of Lard
Makes the player fat
+2 Max HP (unfilled)
heals 1/2 Heart
-1 Speed

Charm of the Vampire - a black bat
Gives Isaac a single fang and a tuft of black widow's peak, makes his face pale
Every 13th enemy killed heals 1/2 heart

Chocolate Milk - A glass of chocolate milk
Isaac will spit brown tears
Auto-rapidfire of tears is removed, holding the attack button will charge a
stronger attack

The Common Cold - a glob of green snot
Turns Isaac's face green, he appears sickly
Spits green tears
Tears randomly poison enemies for 2.5 seconds
Unlocked by finding any 2 of the following items in any one playthrough: The
Virus, Roid Rage, Growth Hormones

The Compass
Shows the locations of the Boss Room, Arcades, Treasure Rooms, Shops, Mini-Boss
Rooms on your map. Does not reveal the map layout.

Cupid's Arrow - an Arrow
Adds a headband with a feather to Isaac's head
Tears pierce enemies but lose knockback effect.

Dessert - A bag of dog food
+1 Max HP

Dinner - A can of dog food
+1 Max HP

A Dollar
+99 pennies (max)
Dropped by the Slot machine when jackpot is rolled

Dr. Fetus - A Fetus in a Jar
Grants Isaac the iconic Top Hat and Monocle
Reduces firing rate
Replaces tears with bombs that slide over pits and can be pushed around (still
hurts you if caught in blast)

Growth Hormones - a purple syringe
Large growths on Isaac's face/head
+2 Damage
+2 Speed

The Halo
Gives Isaac a Golden Halo
+1 Damage
+1 Max HP
+1 Speed
+1 Tears
+1 Range
Unlocked by defeating the 2nd floor Chapter 3 or 4 boss with the Bible item
(instantly kills that boss when used)

The Inner Eye - A White eye
Gives Isaac an open third eye on his forehead
Reduces tears stat to minimum
Fires 3 tears in a triangle formation with each shot
Triples the damage for Technology and Brimstone but minimizes firing
speed/charge time

The Ladder
Allows the player to cross over pits where they are only 1 space wide.

Lokis Horns - A small set of horns
Give the player short horns
Occasionally fires 4 tears in a + pattern instead of a normal attack

Lord of the Pit - A Black inverted Cross
Turns the player black and grants Demon Wings
Allows the player to fly
Allows the player to bypass Arena doors

Lucky Foot - A foot with an attached ring
Puts a gold ring around Isaac's left foot
Random unidentified pills always have a positive/neutral effect
Raises the chance of finding items in fires/poo piles
Raises the odds of winning the Skull game to 50%
Golden chests drop treasures more frequently
Cain starts with this item
Unlocked by having $0.55 or more at any time during a playthrough

Lunch - a dog bowl
+1 Max HP

A Lump of Coal - A black rock
Stains Isaac's face with coal
Turns tears black
Tears grow in size and do more damage as they travel farther
Unlocked/dropped by defeating Krampus

Magic Mushroom - A red spotted mushroom
Isaac gets much bigger
Fully heals the player when picked up
+1 Max HP
+1 Damage
+1 Speed
+1 Tears
+1 Range

Magneto - a magnet
Puts a magnet on Isaac's head
Attracts coins, hearts, soul hearts, bombs and troll bombs to the player when
close enough. Items will move through all obstacles.

The Mark - a triangle of 6s
Puts the Mark on Isaac's forehead
+2 Damage
Grants a Soul heart

Max's Head - a puppy's head
Isaac's eyes grow bigger and sadder
+1 Damage
Bigger tears

Mini Mush - a small blue mushroom
shrinks Isaac
+1 Speed
+1 Range

Mom's Contacts - A red eye
Gives Isaac a red contact with eyelashes
Turns tears bright red
Randomly petrifies enemies for 2.5 seconds when they are hit
Unlocked by finding Mom's Eye and any other "Mom's" item in one playthrough

Mom's Eye - a white eye with eyelashes
Gives Isaac an eye in the back of his head
Randomly fires a tear backwards each time you attack

Mom's Heels - Red pumps
Gives Isaac red heels on his feet
+2 Range

Mom's Knife
Gives Isaac Mom's skirt and knife held in front of him
Replaces Isaac's tears with Mom's Knife
Enemies touched by the knife take damage
Knife can be charged and thrown, more charge sends the knife farther, deals
more damage when thrown
Overrides ALL attacks
Unlocked by completing chaper 5 with Isaac

Mom's Lipstick
Gives Isaac lipstick
+1 Range

Mom's Underwear
Give Isaac girl's underwear
+1 Range

Money=Power - a $ symbol
gives Isaac $-$ glasses
+1 Damage per 10 coins carried
Unlocked after completing chapter 4 8 times

Mr. Mega - a Big Bomb with an angry face
Gives Isaac a grey helmet identical to Wrath, his head shakes rapidly
All bombs dropped/fired turn into Mr. Mega/Mr. Boom Bombs with a larger
+5 Bombs on pickup
Unlocked by using many bombs across many playthroughs

My Reflection - A cracked mirror
Puts a blue u on Isaac's forehead
Reduces range to default, halves overall max range
Tears will travel to the end of their range and will return to the player
before falling
Returning tears will always return on a path that homes with the player, if the
tear travels past the player it will return again.

Number One - a yellow tear
Isaac smiles!
Turns tears yellow, tears now come from Isaac's body and he closes his eyes
while firing
Reduces Range to minimum
Increases Tears to maximum

Odd Mushroom (1) - A thin, shrivelled mushroom
Shrinks Isaac's head
Randomly causes any combination of the following:
+1 speed
Max Tears
-1 Max HP
-1 Damage

Odd Mushroom (2) - A fat mushroom with a wide cap
Makes Isaac's head bigger
Randomly causes any combination of the following:
+1 Damage
Overall size increase
+1 Max HP

Ouija Board
Removes Isaac's eyes and makes his face pale and wailing, no longer cries
Tears travel through terrain and obstacles but NOT enemies
Reduces damage against poo piles, explosives and fires

The Pact - A blood soaked paper
Turns Isaac black and gives him small horns and an aggressive look
+1 Damage
+1 Tears
Adds 2 Soul Hearts

The Parasite - A pink slug
Puts a parasite on Isaac's head
When tears hit an obstacle that stops them, they will split in two and fire out
at 90 degree angles
Unlocked by collecting any two of the following in one playthrough: Bob's
Rotten Head, Tammy's Head, Max's Head, Guppy (Dead Cat)

Gives Isaac two large horns
+2 Damage
Increases the odds of finding a Devil room after each boss is defeated

Gives Isaac a surgeon's mask
Identifies pills after a short waiting period after pickup
Pills consumed always have positive effects of neutral effects (-1 stat effects
become +1, Bad trip becomes full health)
Blood Donation Machines drop a higher average amount of cash per use

A Quarter
+25 coins
Unlocked after completing chapter 4 4 times
Note: this item can be found in shops, in which case it will ALWAYS give a
profit when purchased.

Raw Liver
+2 Max HP
Restores HP to full
-1 Range

Roid Rage - a green syringe
Gives Isaac a roid rage face
+2 Speed
+2 Range

Rosary - a set of beads with a cross
Gives Isaac a small cross necklace
Grants 3 soul hearts
Bibles appear more frequently in shops and sometimes as treasures

Rotten Meat - a chicken leg
+1 Max HP

The Sad Onion
Isaac Cries MUCH Harder
x2 Tears

Skatole - A fly with a heart above it
Gives Isaac a pile of poo on his head
Converts attack flies into normal flies
Normal flies do not deal touch damage
Pooters no longer deal touch damage and will not attack
Boom Flies/Bloat Flies are slowed
Moters do not deal touch damage and do not spawn attack flies when killed
Rewarded by the Shell Game

Skeleton Key
Gives Isaac a keyhole on his forehead
+99 Keys

Small Rock
Jams a rock into Isaac's skull
Turns tears grey
+2 Damage
+1 Speed
Can only be found in Magic Rocks
Unlocked by blowing up 50 rocks across any number of playthroughs

Spelunker Hat
Gives Isaac a Spelunker Helmet
Shows if adjacent rooms are Mini-Boss or Secret Rooms
Unlocked by completing the Caves

Spider's Bite - A black spider
Gives Isaac a spider bite on his head
Tears will randomly slow enemies for 2.5 seconds when hit

Spoon Bender - a Bent silver spoon
Gives Isaac a purple glowing gemstone in his forehead, closes his eyes
Turns tears purple
Tears home in on enemies, will curve and turn around to hit enemies.

Steam Sale - a 50% off coupon
Hangs a coupon from Isaac's right ear
All items in Shops are at sale price (red)

Steven - A Black Face
Gives Isaac a small face sprouting from his head
+2 Damage
Steven will randomly drop this as well and will always drop this if the player
already has Little Steve

Super Banadge
Isaac Wears a bandage on his head and Bandage Girl's flower
+1 Max HP
Adds 2 Soul Hearts
Unlocked by defeating all 4 horsemen in one playthrough

Technology - a cyborg eye
Give player the technology bionic attachment
Gives Isaac Lasers instead of a tear, which always comes from the Technology eye
Lasers pierce enemies (but not terrain) and no longer knock back enemies

Transcendence - a noose
Removes Isaac's body (if Isaac is black from a demon effect, he will have wings
Allows the player to fly
Can bypass arena doors
Only found in secret rooms
Unlocked by completing chapter 4 2 times

Treasure Map
Reveals the floor layout and the location of the Secret room

The Virus - Red Syringe
Isaac looks infected and is covered in boils and sores
Touching enemies damages them and poisons them for 2.5 seconds

The Wafer
Grants Isaac a blue aura
Reduces all damage to 1/2 heart or half of it's assigned value (ie the Razor
Blade in later chapters)
Note: this item reduces all purchases in the Devil Room with ??? to 1/2 of one
soul heart
Unlocked by completing chapter 4 7 times

The Whore of Babylon - a Black Moon and Star
Activates when the player's HP is exaclt 1/2 of one heart (soul hearts are
ignored, making this item VERY useful for ???)
When active, the player turns into the "Whore of Babylon" with curvy horns,
sharp teeth, black skin and a red cross on the forehead
When active, multiplies the current damage dealt by players (exact amount
Effects wear off when the player has 1 HP or more

Wiggle Worm - a blue worm thing
Isaac's head shakes rapidly
Tears travel faster and fire along a wavy path.
Tear paths are no longer effected by player movement

Wire Coat Hanger
Jams a coat hanger through Isaac's head
+2 Tears

Wooden Spoon
Gives Isaac beat marks from the spoon
+2 Speed

X-Ray Vision - glasses with eyes on them
Gives Isaac X-Ray glasses
Allows the player to pass freely into adjacent secret rooms (will appear as
holes in the wall) and also exit secret rooms into any adjacent room.

These treasures follow the player or orbit around you.
Familiars that attack with projectiles will attack when the player attacks.
You can have a maximum of 3 close orbitals.
Two orbitals will be opposite one another, three will be spaced out at 120
degrees from one another.

1UP - A green spotted mushroom
Follows the player
Grants the player an extra life - if you die it will be consumed and you will
respawn in the previous room with full HP.
Appears only in secret rooms

Guppy ("Dead Cat") - A Dead Black cat
A floating cat head follows the player.
Grants 9 lives total.
Reduces HP to 1 when obtained.
Reduces HP to 1 when the player respawns.
-If the player dies when picking this item up (when purchased from Satan), it
will count as a respawn using the item.

Dead Bird - A dead black bird
When obtained, is worn on the player's head.
If at any time the player receives damage, for the duration of the room, the
Dead Bird comes to life and attacks enemies in the room.
Flies over obstacles.
-Unlocked with Eve
-Eve Starts with this item

Bomb Bag - A Small sack with a bomb on it.
Follows the player
Drops a random bomb item (Bomb, 1 +1 Free, Troll bomb) after every 3 rooms
Unlocked by completing chapter 5 with Cain

Sack of Pennies - A small sack with a penny on it
Follows the player
Drops a penny or nickel after every 2 rooms completed.
Unlocked by completing chapter 4 with Cain

Little C.H.A.D. - A small C.H.A.D.
Follows the player
Drops a half heart after every 2 rooms completed.
Unlocked by defeating C.H.A.D. in the caves
Always dropped by C.H.A.D.

Halo of FLies
Grants 2 Pretty Flies to the player

-Pretty Fly-
Close orbital
Obtained by either "Halo of Flies" Treasure, a random reward from a slot
machine, or from a Pretty Fly Pill

Forever Alone
Grants a distant blue attack fly that orbits the player, farthest orbital.
Damages enemies on contact.

Distant Admiration
Grants a semi-distant red attack fly that orbits the player, intermediate
distance. Damages enemies on contact.

The Relic - a Blue Cross
Follows the player
Drops a soul heart every 4 rooms.

Follows the player
Fires a small laser (see Technology) with the player.
Unlocked by completing chapter 4 with Judas.

Little Steve
Follows the player
Fires homing shots (see Spoon Bender) with the player
Unlocked by defeating Steven
Frequently dropped when Steven is defeated as a boss in the Basement

Little Gish - a tiny Gish
Follows the player
Fires tar shots that slow enemies with the player.
Unlocked by defeating Gish
Always dropped when Steven is defeated as a boss in the Depths

Little Chubby - a miniature Chub
Follows the player
When the player attacks, he will fly forward and attack all enemies he touches,
then will return to the player.
Unlocked by defeating each of the normal bosses in the caves at least once
across any number of playthroughs.

Guardian Angel - a small angel
Close Orbital
Speeds up all other orbitals controlled by the player
Unlocked by completing chapter 5 with Maggy

Demon Baby - A small black demon
Follows the player
Automatically attacks all nearby enemies with rapid firing, short range blood
Unlocked by completing chapter 5 with Eve

Brother Bobby - A small blue spirit.
Follows the player
Spits small tears

Sister Maggy - A small red spirit.
Follows the player
Spits small blood balls (greater damage)

Cube of Meat - A red cube
Close orbital.
Similar to pretty fly.
Can be obtained multiple times.
2nd pickup changes the cube into a floating head which fires blood balls with
the player.
3rd pickup changes the head into a mini Super Meat Boy familiar that follows
the player and attacks enemies with touch damage (loses ranged attack)
4th pickup enlarges Super Meat Boy and increases the damage he deals.
-Dropped by Riders or the Headless Horseman
Through exploitation of the Dice and the Forget Me Now, more than 4 cubes of
meat can be obtained in one game. Additional cubes can generate a second
orbital once the first is completed and more than one Meat Boy can be created,
though this is rare and difficult.
Unlocked by completing chapter 3 once.

--Pills Here!--
There are 6 different pills in the Binding of Isaac, when a pill is found it is
randomly assigned an unassigned pill effect from the list of possible effects.
Pills are unidentified on pickup and identify when consumed.
Picking up another pill card will drop whatever card or pill you are carrying.

Pill Styles:
1 - All Blue
2 - Half Blue, Half White
3 - All Orange
4 - All White
5 - Half Red, Half Pink
6 - Half Red with the other half filled with Red Pellets

Pill Effects:
"Bad Gas" - The player releases a fart cloud, poisoning all nearby enemies for
2.5 seconds
"Bad Trip" - Deals 1 Damage to the player, if the player would normally die
from this effect, they are granted Full Health instead.
"Balls of Steel" - +2 Soul Hearts
"Bombs are Key" - Exchanges Keys and Bombs
"Explosive Diarrhea" - Drops 5 troll bombs at the player's feet as they move
"Full Health" - Restores HP to full
"Health Up" - +1 Max HP
"Health Down" - -1 Max HP, if the player has a Max HP of 1 when consumed, they
get +1 instead
"I Found Pills" - And I Ate Them! Gives the player a dumb look on their face
"Pretty Fly" - Grants 1 Pretty Fly Orbital Familiar
"Range Up" - +1 Range
"Range Down" - -1 Range
"Speed Up" - +1 Speed
"Speed Down" - -1 Speed
"Tears Up" - +1 Tears
"Tears Down" - -1 Tears
"Telepills" - Teleports the player to a random room or to the I Am Error! Room

--Tarot Cards--
There are 22 Tarot Cards total, roman numerals 0 to XXI. They are face down
when dropped and are revealed to the player when picked up.
Picking up another tarot card will drop whatever card or pill you are carrying.

0 - The Fool - Teleports you to the starting room of the current floor
I - The Magician - Grants homing tears for the current room only
II - The High Priestess - Mom's foot crushes down on a random enemy dealing
massive damage, hit's the player if no enemies are present.
III - The Empress - Turns the player into the Whore of Babylon for one room only
IV - The Emperor - Teleports the player to the Boss Room
V - The Hierophant - Spawns 2 Soul Hearts
VI - The Lovers - Spawns 2 Full Hearts
VII - The Chariot - Same Effect as My Little Unicorn
VIII - Justice - Spawns one of each of the following: a half heart, full heart
or soul heart; a bomb, 1+1 Free or troll bomb; a penny or nickel; and a key
IX - The Hermit - Teleports the player to the shop or a random room if there is
no shop
X - Wheel of Fortune - Spawns a slot machine
XI - Strength - Temporarily mirrors the effect of the Magic Mushroom; effects
wear off after one room. (The +1 max HP stays if you are ???)
XII - The Hanged Man - Removes the player's body and grants flight for the
current room only.
XIII - Death - Deals heavy damage to all enemies in the room.
XIV - Temperance - Spawns a Blood Donation Machine
XV - The Devil - Damage multiplier, same effects as the Book of Belial
XVI - The Tower - Spawns 6 troll bombs in the room
XVII - The Stars - Teleports the player to the Treasure Room. Random teleport
if none exists.
XVIII - The Moon - Teleports the player to the Secret Room
XIX - The Sun - Combined effects of Full Heal, the Death Tarot, and the World
XX - Judgement - Spawns a Beggar
XXI - The World - Reveals the entire map and every room in it, including the
secret room.

Achievements/Unlockables       |

These grant "secrets" in your stats section, of which there are many!


The Following Secrets are also Achievements in the Steam Browser.
The Radioactive Spider
Complete the Basement!
Finishing the Basement II
Unlocks the Spider's Bite treasure

Monstro's Tooth
Defeat all bosses in the Basement!
Beat each of the 4 major Bosses in the Basement
Unlocks the Monstro's Tooth treasure

The Spelunker
Complete the Caves!
Finishing the Caves II
Unlockes the Spelunker Helmet Treasure

Lil Chubby
Defeat all bosses in the Caves!
Beat each of the 4 major bosses in the Basement
Unlocks Lil Chubby treasure

I Killed Mom!
Kill Mom...
Finish the Depths II
Title screen change (Isaac beats mom!)

Loki's Horns
Defeat all Bosses in the Depths!
Beat each of the 3 Major bosses in the Depths
Unlocks Loki's Horns treasure

The Rock
I Like to break things...
Destroy 50 stones
Unlocks the Small Rock treasure

The Bean
You don't wanna know where this has been...
Destroy 50 poop piles
Unlocks the Bean treasure

Mom's Pill Bottle
Mom needs her pills! Donate blood
Donate blood 20 times
Unlocks Mom's Pill Bottle treasure

The Gamekid
I lost mine in the arcade...
Enter 10 arcades.
Unlocks the Gamekid treasure

The Common Cold
Dirty needles.... eww
Collect any 2 of the 3 syringe items in one game: The Virus, Roid Rage, Growth
Unlocks the Common Cold treasure

Mr. Mega!
Kids shouldn't play with matches...
Destroy 10 magic rocks
Unlocks Mr. Mega treasure

The Book of Sin
Destroy the 7 Sins...
Defeat each of the 7 Deadly sins at least once each
Unlocks the Book of Sin treasure

Mom's Contacts
Stay out of Mom's things!
Collect Mom's Eye after collecting any other "Mom's" item in the same game
Unlocks Mom's Contacts treasure

The Parasite
Kids shouldn't play with dead things...
Collect any 2 "dead things" in one game: Max's Head, Tammy's Head, the Dead
Cat, Bob's Rotten Head.
Unlocks the Parasite treasure

The Necronomicon
Call death upon all of them!
Use the Death Tarot card 4 times across any number of games.
Unlocks the Necronomicon treasure

The Halo
Give Mom a taste of her own medicine!
Defeat Mom or Mom's Heart using the Bible
Unlocks the Halo treasure

The Bandage
Make Super Meat Boy!
Defeat each of the 4 riders in any one game (Famine, Pestilence, War AND Death)
Unlocks the Super Bandage treasure

The Shears
I've lost my head one too many times...
Die 100 times
Unlocks the Pinking Shears treasure

Maggy's Wig
At any time, have a max HP of 7
Unlocks Maggy and the Yum Heart treasure

Cain's Eyepatch
At any time, have 55 coins or more
Unlocks Cain and the Luck Foot treasure

Judas' Fez
Finish the boss in the second floor of Chapter 4
Unlocks Judas and the Book of Belial treasure. Changes the Title Screen (Broken

Eve's Dead Bird
Purchase 2 items from the devil in any one playthrough
Unlocks Eve, the Dead Bird treasure and the Whore of Babylon treasure

My Head Hurts...
Defeat Steven
Unlocks Little Steven treasure

I need a hug...
Defeat C.H.A.D.
Unlocks Lil C.H.A.D. treasure

I Have Sticker Fingers...
Defeat Gish
Unlocks Little Gish treasure

The Noose
Finish Chapter 4 a second time
Unlocks Transcendence treasure

The Nail
Finish Chapter 4 a third time
Unlocks the Nail treasure

The Quarter
Finish Chapter 4 a fourth time
Unlocks the Quarter treasure

The Fetus
Finish Chapter 4 a fifth time
Unlocks the Fetus in a Jar treasure

Everything's Terrible
Indeed it is...
Finish Chapter 4 a sixth time
Increases overall difficulty of the game, changes some in game odds, etc.

The Wafer
Finish Chapter 4 a seventh time
Unlocks the Wafer treasure

Money = Power
Finish Chapter 5 an eight time
Unlocks Money=Power treasure

It Lives!
Finish Chapter 5 a ninth time
It Lives! will now be the boss of the second floor of Chapter 4. Changes Title
Screen (Isaac in the Womb)

Defeat It Lives!
Unlocks ??? and the Poop treasure. Changes Title Screen (Dead Baby)

The Bag
Complete chapter 4 with Cain
Unlocks the Sack of Pennies treasure

The Robo-baby
Complete chapter 4 with Judas

The Cross
Complete chapter 4 with Maggy
Unlocks the Relic treasure

The D6
Complete chapter 4 with ???
Unlocks the D6 treasure, Isaac now starts with the D6.
The Razor Blade
Complete chapter 4 with Eve
Unlocks the Razor Blade treasure

The Bomb Bag
Complete chapter 5 with Cain
Unlocks the Bomb Bag treasure

Mom's Knife
Complete chapter 5 with Isaac
Unlocks Mom's Knife treasure

Forget Me Now
Complete chapter 5 with ???
Unlocks the Forget Me Now treasure

The Monster Manual
Complete chapter 5 with Judas
Unlocks the Monster Manual treasure

The Guardian Angel
Complete chapter 5 with Maggy
Unlocks the Guardian Angel treasure

The Demon Baby
Complete chapter 5 with Eve
Unlocks the Demon Baby treasure

A Gift from Krampus
Find and defeat Krampus
Unlocks the Lump of Coal treasure

Basement Boy
Complete Basement without taking damage

Spelunker Boy
Complete the Caves without taking damage

Dark Boy
Complete the Depths without taking damage

Mama's Boy
Complete Chapter 4 without taking damage

Golden God!
100% the game!
Collect every treasure excluding the Dollar and the Shears
Changes Title Screen (Golden God!)

The following are not Steam Achievements, but are still in Game Secrets
Something from the Future - Complete the Basement many times - Unlocks Steven
Something Cute - Complete the Caves many times - Unlocks C.H.A.D.
Something Sticky - Complete the Depths many times - Unlocks Gish
A Cube of Meat - Complete Chapter 3, the Depths - Unlocks the Cube of Meat
The Horsemen are Loose! - Complete Chapter 3, the Depths - Unlocks the Riders
and the Headless Horseman
Mother Sleeps - Complete Chapter 3, the Depths - Unlocks Chapter 4

every item unlocked with a character is also a secret found, there are a total
of 63 secrets in game at the moment.
NOTE: Chapter 5 has no official achievement unlocking it, instead, to reach it,
the following conditions must be met:
A) Complete chapter 4 with all of your Hearts full
B) Complete chapter 4 after unlocking Everything's Terrible (raises odds
C) Dig past Chapter 4's 2nd floor using We Need to Go Deeper

Finishing Chapter 5 counts as an additional completion of chapter 4 in terms of
achievements and rewards.

Starting in the basement I as Isaac...
I have 3 options, N, S, and W.
Head North.
Room contains 2 Gapers and some poop/rocks, another door leads E. After
clearing both Gapers (and their subsequent gushers) I am rewarded with 1/2 a
heart and another 1/2 heart from a poop pile.
Head East.
Room contains 4 Gapers enclosed in a stone circle with an opening, as the pour
I out I pick them off. 1/2 Heart reward.
Return to start point, head South.
Room has 2 Mulligoons and a path East. 1 Key reward.
Head East.
Room has 6 Pacers and a gusher, also rocks enclosing a chest. Path East to Shop
and South to Treasure Room. Penny reward.
Head South.
My treasure is the Charm of the Vampire! 2 Fires in the room contain 1 full
heart and a penny.
Head North into previous room, bomb North seeking Secret Room. Found it!
Secret Room contains 6 Pennies.
Return to start room.
Head West.
Room contains a pooter surrounded by 4 flies. Dodge behind rocks and pick them
off, 1 penny reward. Path West.
Continue West.
Room contains a Stone circle with 2 pennies, a nickel and a magic rock... no
bombs, curses! I'll check the shop after the boss.
Head south to boss room.
(See boss section)
Take 1/2 heart damage but I'm rewarded with a full heart and a Cube of Meat!
Head back to check out the Shop, I have 9 coins. Shop has 2 treasures and a
soul heart... no bombs. Curses. Take the soul heart for 5 coins.
Return to the trapdoor. Current loadout: 2 treasures, 4 coins, 3 HP and 1 SP.
Final floor layout:
B   R-R-$

Off to an OK start, could have done better if I looked for the secret room
later than sooner.
Land in a room with 3 paths, N,S,W
Head North.
2 Clotties, stones and paths N and E.
The bloodbath leaves me taking 1 full heart of damage (accursed clotties!) 1
full heart reward... should have saved those 5 coins...
Head East.
Room has path E, 1 clotty. 1 Key reward
Continue East.
Empty room with Flaming Pentagram. Path N to shop, S to another room. Fires
contain nothing :/
Continue South.
The battle costs m 1.5 hearts, but gives me back just as much in return. No
treasures from the fat little jerk... Return to a previous room (N, W,W)
Heading North.
Dead end with a Clotty and 2 flies. 1 coin found in a poop pile.
Return to Start point, head South.
Path south, room contains 4 gushers and 4 Gapers held at bay with poop piles,
one is a champion Gaper. 1 coin from the champion gaper and another 1 coin
rewarded from the room itself. Magic Rock spotted and noted mentally.
Head South.
Path W to Treasure Room, E to Boss Room. Room contains a pooter, gusher, clotty
and horf... oh my. They are sectioned off by a + of rocks, time to take them
one at a time. 1 penny and 1/2 heart reward in center of rocks... not worth it.
Unlock Treasure room....
Anarchists Cookbook! Pretty Lame for a treasure, but I'm low on bombs so it's
pretty handy.
Return E and N to the room with the Magic Rock. Release my Anarchist's
Cookbook... blows up everything BUT the magic rock :/, off to explore the path
West from the start.
Empty room with a normal chest. Contains an Orange pill... Explosive Diarrhea :/
Head to the Boss...
Vs. Monstro!
He has 2 flies with him... pfft, this should be easy.
Take 1/2 heart getting cocky at the end but I'm rewarded with a full heart and
the coveted Super Bandage :D
Current Loadout:
4 Treasures, 7 coins, 4 HP and 2 SP
Floor Layout:

  R   $
R-R   b

Could be doing much better with some predictable bombs, but no such luck. BOI
seems to be taunting me here trying to blow me up but nothing else...

Paths in all 4 directions... ooh boy options... Head N to start.
Path North to Treasure room; 3 Sealed maws (one champion) and two moters. Take
1/2 SP damage from an attack fly as it comes from the Moter, rewarded with a
key and a chest. 2 coins and a Full Heart in the chest.
Unlocking my Treasure...
My Little Unicorn... what a joke. My least favorite item. At least I score one
coin from a nearby fire.
Return to start, head south.
3 Hosts on an island. 1/2 SP damage from a wave of blood spewed at me... no
Return to start, head East.
Locked Chest on an island, rocks to build bridges (but no BOMBS :/) path East.
Continuing East.
A Hive on an island, path S to shop, E to another room.
Continuing East.
Dead End with 2 Hives. 1/2 SP damage from a fly spat at me, but 1+1 free bomb
as a reward. YES! My cookbook is ready to go...
Return to room with chest and unleash my cookbook. I create a bridge by luck,
but miss the potential door to a possible secret room. Will return with a key
Head West from Start
Path West, 2 moters, 1 Hive. 1 Coin reward.
Heading West.
4 Maws (crud!) plenty of pits to keep me from dodging (double crud) and paths N
and W. Lost my last SP, a troll bomb reward (really...)
Head North.
My slow speed costs me a full heart of touch damage, but I get a B/W pill
reward... Speed+, yays.
Return to last intersection and head West.
2 Maws. Path W to boss, S to arena. 1 Coin reward. Arena remains locked, to the
VS GURDY (crud...)
Fortunately/Unfortunately this seems to be the Champion DARK Gurdy... less
dodging but more killing. I use my Cookbook right off the bat. The rest of the
fight is a long, toilsome killfest. Unrelenting pooters bring me down to 1.5
Hearts, +1.5 from the boss and mom's underwear to boot.
Return and guess/find the Secret room which nets me 6 coins. A left behind full
heart brings me to 4 HP and opens up the arena...
Normal chest... 1 Bomb and 1 full heart :/ between my charm and the heart I
don't lose any HP overall. I curse my misfortunes and delve deeper.

18 coins, 2 bombs, no keys. 4 HP and 5 treasures. Not too happy. Base stats...
+1 Speed and +2 Range though. Not going to help me kill anything though.
    b ?-R
  A     R   $

Paths N, W and E.
Head North.
Path north and Champion Globin. 1 Bomb and 1 coin rewards.
Head North.
8 Spitties on islands, 2 are champions. 1/2 Heart reward plus 2 keys I can't
reach :/ Path East.
Heading East.
Dead end, 3 globins. Chest reward... 7 coins total (2 pennies + nickel :D) Try
to bomb south but no secret room there.
Return to start and head East.
Empty room with 1 coin surrounded by spikes... not worth it. Paths south and
Heading east.
Locked shop to the north, 3 spitties, 2 hives (1 champion) all on an island.
Cookbook wipes them all out but strands my reward of a key and bomb on the
island (all my hate).
Backtrack and head south.
Path south to locked treasure room. Same layout as previous room (eh?) Still no
keys and my rewards are 1.5 hearts I don't care to grab. Locked out of all the
good stuff arg...
Return to start, head west.
Paths south and west, 3 hives to deal with. 1 key reward, yay! Saving it for a
later choice of options.
Head south.
Path south, 2 hives and a host on an island. Cookbook makes them all go away
but costs me 1 heart of blast damage.
Head south.
Path south, 2 hosts and a flesh host on an island blocked by rocks. Lose 1/2
heart and no reward.
Head south.
2 Troll bombs reward, thanks alot you jerk. Charm and damage leave me with an
overall 2.5 out of 4 HP.
Backtrack North twice, check for a secret room. Found it! 3 Coins reward, pfft.
Return to the junction leading west and explore.
8 Spitties and no cover... Full heart reward, damage and self heal leaves me at
3 HP. Path North and West.
Heading North.
Boss up North.
5 Spitties and even less cover/moving space. 1 Bomb reward!
Return to the junction and head west.
3 Clotties on an island, path west to Arena. Self heal to 3.5 HP, a Speed+ Pill
lands on the island... MINE!
Grab an abandoned heart from another room and return to the Arena.
Normal Chest... 1 coin and 1 key, 2 bombs final reward and leaves me at 2.5 HP.
Ouch... worth it!
Back to my Treasure/Shop... Ouija in the Treasure room.
Now for the shop...
Compass @ 15 coins, key for sale @ 3... BUYIN EM!
To the Boss!
VS Pestilence (thank you!)
2nd cube of meat means a fighting familiar to help me out!
Current layout:
13 Coins, 3 Bombs, 1 Key, 8 Treasures, 2.5/4 HP, 4 Speed, Base attack/fire
rate, 4 Range. Plus meat boy's head!

Forgot the map, sorry...

Land in the Depths 1
My compass tells me the shop is NE, the Treasure is NW, the boss is E and the
Miniboss is W.
I can go S,W and E.
Heading W.
Path N, W and a Leech to deal with. A +Speed Pill reward!
Head North.
Dead end with 2 Blast flies and 3 Boils, 1 fly is a champion. Boils die first,
flies next. 1 coin and 1 bomb reward.
Backtrack and go West.
2 Guts in a pit maze, 1 key reward, paths south and west.
Going west.
5 Vis, path north and west. Use my cookbook but take a little damage. 1 Bomb
reward; total HP 2.5/4.
Head north.
3 Sentries, 2 boils, path north to treasure room as promised. 1 Bomb reward.
Treasure... GUARDIAN ANGEL (yays!)
Backtrack and head west.
4 Knights, path south to miniboss; erratic Knights cost me some HP... down to
1/4 :/
Going south...
2 Bombs and a coin reward... close call.
Search for secret room... 2 failures, head to previous unexplored junction and
head south.
4 More knights, going to be careful this time.
No reward, heading south.
4 Hoppers, 1 Leaper. Dead end and a troll bomb reward. Backtrack and keep
looking for secret room. 1 try, 1 failure.
Backtrack and head south at start.
Dead end,2 Globins, 3 hemoglobins, 1 champion of each... this could be the end.
SAFE! +1/2 Hp from the charm, 3 bombs reward.
Backtrack, head east.
2 suckers, 2 medium Fistulas. Paths north and east. Now at 2/4 HP from healing.
Head north.
2 Sentries, 3 Brains (1 champ) path north to shop. Full heart reward, shearch
for secret room... 2 tries, 2 fails. Into the shop.
White pill @ 3 coin sale and Lemon Mishap at 15 coins, buy the pill...
Telepills, return to shop again and put out fires.
Backtrack, head east.
Paths east and south. 3 Brains, 2 sentries. 1 Coin reward. Head south.
3 Boils in a spike maze... 1 HP reward. Search for secret room... FINALLY...
A slot machine... ouch. Gamble down to 7 coins and score 2 bombs and some
hearts. At max HP now. Blow it up... Explosive Diarrhea Pill... I'll hold on to
Backtrack and head east.
6 Boils, 1 champ, path east. The bloodbath costs me a net 1/2 HP loss.
6 Pooters on an island, Ouija makes quick work of them through the rocks. Bomb
on to the island to score 2 bombs and a key.
Boss time!
VS Loki!
Cookbook clears out some rocks and hurts him a bit... finish him off unscathed
rewarding me with Rotten meat and a Devil Room...
Satan offers me Sister Maggy for 3 Soul hearts (I have none :/) and the Mark
for 2 HP... WORTH IT!
Loadout and stats:
11 Treasures, 7 coins, 8 bombs, 1 key, a stored pill (diarrhea), MAX Speed, 2
Tears rate, 4 Attack, 4 Range, 3 HP 1 SP.
Floor Layout:

  T       $
  R   R   R
b   R   R   R-? B

Last floor of a basic runthrough!!
The Depths 2!
The compass alerts me to a Treasure room (W), miniboss room (W, directly S of
Treasure), boss room (SW), shop (E), arcade (S) and arena (SE) on this floor...
this is going to take a while. Since the miniboss room is directly south of the
treasure room I am going to assume it is greed in a secret room, I'll be sure
to pay him a visit.
Paths head N, W and E
Going north...
Slot machine on an island... path north.
Going north.
Path West, 2 leeches. Lose my SP to a leech, gain 2 bombs.
Head West.
Dead end, 3 vis, 1 is a champ.
Current loadout, 8 coins, 10 bombs, 1 key... return to start and head west.
Pokies, 2 babies, a boil and pits... a path south. A stranded key reward.
Heading south.
2 Mini blastocysts. Path west. 1 Bomb reward.
Going West.
Path south and another West to the Treasure room. That miniboss is 100% a Greed
in a secret room, I'll visit him in a bit... Flesh host on an island, 4 pokies.
stranded key reward.
My treasure is... Mom's Pill Bottle. Use it once for +speed pill. Keeping this
bottle instead of the book for now.
Greed time!
1 Bomb entrance fee, 1 heart damage, now I'm up to 18 coins thank you very
Backtrack to start.
Going east.
Path east and south, magic rock spotted and a couple of suckers. 2 Soul hearts
from the rock.
Heading east.
Path east, 4 sentries, 3 leapers, 1 is a champ. Costs me a soul heart but gives
another back. Almost to the shop, one room to go.
Heading east.
4 Babies. 1 coin reward... but I have no keys to enter the shop... backtrack
and head south.
Chub and a path south. Feed on his young and feed him a bomb for a key and half
a heart. Going to the shop!
Buy the book of Revelations for 7 coins. +1 SP from the book right off the bat,
going to recharge it hopefully before I meet up with the boss.
Backtrack to the path south, heading towards the arena.
Path east, path south to arena. 3 Knights, 1 champ knight, 1 Knightmare. Use a
bomb to clear some breathing room, lose 1/2 SP and gain a few coins.
Into the arena.
Locked Chest... I'll be back.
To the east.
3 Bloat flies and a few sentries. Charm heals me back to full HP, 1 key
reward... to the Arena again!
A card of temperance is my reward... the battle leaves me with 3 HP, 1.5 SP and
a bomb... using the card generates a blood donation machine which instantly
yields a blood bag after 1 use (zomg lucky!) +1 Max HP for me!
Backtrack to the room outside of the treasure room.
Head south.
Path South, 5 mr. Maws.
Head south again.
4 Babies, door to arcade is east, path west the boss is farther west still.
Lose 1/2 SP to being WAAY too fast and gain a bomb... entering the arcade.
No need for cash, time to gamble! 2 Keys, Skatole and all my coins are now
gone... now to the blood bank. 2 HP nets me 9 coins... 9 coins nets me 1 Heart
and a HP+ pill... 1 HP spent gets me 2 more coins. 2 coins gets me back 1 HP...
which gets me 2 coins which get me nothing. Leaving for now, heading to the
pre-boss room.
3 Flesh hosts and 2 pokies. Recharges my Book and grants me 1/2 HP from the
charm... going back.
1 more use of the blood donation machine finally yields another blood bag,
which increases my max HP by 1 and heals back all my losses.
Blow up the slot machine... get 2 more bombs back... on to the boss.
My loadout was not really that good for dealing heavy damage and the battle was
costly. Mom leaves behind a Wire Coat Hanger leaving my stats at:
15 Treasures, 0 Coins, 10 Bombs, 2 Keys, 1 Pill (diarrhea), plenty of abilities
and 2 familiars.
My post-mom stats are: Max Speed, 4 Tears Rate, 4 Attack, 4 Range. 1.5/6 HP and
the book of Revelations which means for me plenty of SP to come.

  T-R-R-R   R
  b-R       R-R
B-R-R-@     A

I'm gonna stop here and let you explore the rest of BOI yourself, know that
your run through the game will be entirely different in every way. At least
this will let you know what to expect.

View in: