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The only way I found is that you have to stop scrambling completely, then if you're lucky and don't get crushed, you can throw the ball. Why this game doesn't let the qb throw on the run is beyond me. You're better off picking one or the other, as you won't have time to stop scrambling and then throw the football most of the time.
My highlights:http://www.youtube.com/watch?v=2UxvGg7nye0 horrible glitch: http://www.youtube.com/watch?v=PAlXwetiyEwz