That I can't tell you, as I generally don't pay too much attention to trophies and difficulty is subjective. But from looking at the list just now, I'd say there are some that have a fair degree of luck involved, and some that require a bit of grinding to acquire resources for various trophy related purposes. I'd say more time consuming rather than especially difficult.
Overall, I love it because the gameplay is fun and exciting and it keeps you on your toes. You basically have an alien armada chasing you as you jump from zone to zone, so if you hang around too long in one place, they catch up and it's up to you to fight or flee. There's a lot of flexibility in how you outfit and upgrade your ship, and it's a gorgeous looking game too. If you like dogfighting and roguelikes, you'll probably enjoy this.