Hostile Environment means the location itself is fighting you in some way.
And falling does not count - by itself (so King's Quest I's Land of the Clouds doesn't count)
I know I don't have many right now, but if this is a good list idea, then I would be grateful for assistance.
Also, if someone already did this list, then point it out to me.
Here's what I have so far:
Planetfall (PC) - old all-text Infocom game - Resida has disease and mutants (both of which contribute to hostile environment)
King's Quest V - the forest maze had at least one carnivorous, man-eating plant in it
Pikmin - Oxygen was very poisonous to Olimar's species
11th Hour - The house is hungry...
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