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If you haven't done so already, you might play around with the skills trees on the BL3 site to see what options you prefer. It's not fun to sink a bunch of time into a playthrough just to find out that you don't like their skills.
"What's worse, thinking you're being paranoid or knowing you should be?" Primer
Easy Amara for me...I always rock the siren first. I loved Lilith and her laff when she deleted s*** and I know that will probably be the only con with Amara for me since she has a "speak with my fists" personality.