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The O3DS version was my first experience with Terraria and I ended up clocking hundreds of hours on it. I think if I had played the PC version first I might not have liked it as much, but as a standalone game it's pretty great.
And after finishing all the main things in this version I have little interest in playing the PC version since I've already done most of what's available and I prefer handheld gaming anyway. If I was to play a different version I would probably pick the Vita or Wii U ports since I've gotten so used to the touchscreen + physical controls setup.